Recent advances in M2M communications, miniaturized hardware, and microcomputing have spurred the rise of IoT. In healthcare, IoT integration with medical devices has transformed treatment, offering cost-effective solutions, improved monitoring, and personalized care. This has led to complex IoMT systems with unique operating systems and protocols. However, security vulnerabilities threaten their adoption. Research is addressing these challenges by integrating robust security measures. This chapter emphasizes the need for security in IoMT, discussing key aspects and state-of-the-art techniques for securing data transmission, collection, and storage. It explores various security requirements, design complexities, and methodologies to enhance IoMT resilience. Additionally, it surveys current research and suggests future directions for innovation.