AIE-Active Fluorescent Nonconjugated Polymer Dots for Dual-Alternating-Color Live Cell Imaging

Guan, Xiaolin; Lu, Baocui; Jin, Qijun; Li, Zhifei; Wang, Lin; Wang, Kailong; Lai, Shoujun; Lei, Ziqiang

doi:10.1021/acs.iecr.8b03776

Cited by 16 publications

(10 citation statements)

References 46 publications

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“…8 Fluorescent imaging reagents which give cellular images with two different colours, can distinguish sites of interest from false positive signals generated by adventitious fluorescent biomolecules in the monitoring processes. 9 They can also allow for in situ fluorescence based ratiometric reporting of cell conditions such as pH, temperature, hydrophilicity/phobicity, or oxygen concentration.…”

Section: Introductionmentioning

confidence: 99%

Dual emission in purely organic materials for optoelectronic applications

2021

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Section: Introductionmentioning

confidence: 99%

Dual emission in purely organic materials for optoelectronic applications

2021

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“…Conceptually, 50% or more semiconducting polymer (by volume or weight) is important because it distinguishes Pdots as NPs derived from a photoluminescent material rather than a doped host polymer. That said, there are also examples where “Pdot” refers to luminescent NPs composed of non-semiconducting polymer materials where PL arises from cross-link-enhanced emission, − aggregation-induced emission (AIE) Pdots (or AIE dots), , or pendent fluorophores …”

Section: Catalog Of Materialsmentioning

confidence: 99%

Photoluminescent Nanoparticles for Chemical and Biological Analysis and Imaging

et al. 2021

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Research related to the development and application of luminescent nanoparticles (LNPs) for chemical and biological analysis and imaging is flourishing. Novel materials and new applications continue to be reported after two decades of research. This review provides a comprehensive and heuristic overview of this field. It is targeted to both newcomers and experts who are interested in a critical assessment of LNP materials, their properties, strengths and weaknesses, and prospective applications. Numerous LNP materials are cataloged by fundamental descriptions of their chemical identities and physical morphology, quantitative photoluminescence (PL) properties, PL mechanisms, and surface chemistry. These materials include various semiconductor quantum dots, carbon nanotubes, graphene derivatives, carbon dots, nanodiamonds, luminescent metal nanoclusters, lanthanidedoped upconversion nanoparticles and downshifting nanoparticles, triplet−triplet annihilation nanoparticles, persistent-luminescence nanoparticles, conjugated polymer nanoparticles and semiconducting polymer dots, multi-nanoparticle assemblies, and doped and labeled nanoparticles, including but not limited to those based on polymers and silica. As an exercise in the critical assessment of LNP properties, these materials are ranked by several application-related functional criteria. Additional sections highlight recent examples of advances in chemical and biological analysis, point-of-care diagnostics, and cellular, tissue, and in vivo imaging and theranostics. These examples are drawn from the recent literature and organized by both LNP material and the particular properties that are leveraged to an advantage. Finally, a perspective on what comes next for the field is offered.

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“…Due to its dual emission property, blue light at 630 nm and red light at 395nm make it a promising candidate for cell imaging of HeLa cells, A549, and HepG2 cells upon incubation with AIE Pdots. The cytotoxicity studies revealed 90% cell viability Figure 15 [ 91 ].…”

Section: Aie Active Molecules For Biological Cell Imagingmentioning

confidence: 99%

Recent Advances in Aggregation-Induced Emission Active Materials for Sensing of Biologically Important Molecules and Drug Delivery System

et al. 2021

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The emergence and development of aggregation induced emission (AIE) have attracted worldwide attention due to its unique photophysical phenomenon and for removing the obstacle of aggregation-caused quenching (ACQ) which is the most detrimental process thereby making AIE an important and promising aspect in various fields of fluorescent material, sensing, bioimaging, optoelectronics, drug delivery system, and theranostics. In this review, we have discussed insights and explored recent advances that are being made in AIE active materials and their application in sensing, biological cell imaging, and drug delivery systems, and, furthermore, we explored AIE active fluorescent material as a building block in supramolecular chemistry. Herein, we focus on various AIE active molecules such as tetraphenylethylene, AIE-active polymer, quantum dots, AIE active metal-organic framework and triphenylamine, not only in terms of their synthetic routes but also we outline their applications. Finally, we summarize our view of the construction and application of AIE-active molecules, which thus inspiring young researchers to explore new ideas, innovations, and develop the field of supramolecular chemistry in years to come.

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AIE-Active Fluorescent Nonconjugated Polymer Dots for Dual-Alternating-Color Live Cell Imaging

Cited by 16 publications

References 46 publications

Dual emission in purely organic materials for optoelectronic applications

Dual emission in purely organic materials for optoelectronic applications

Photoluminescent Nanoparticles for Chemical and Biological Analysis and Imaging

Recent Advances in Aggregation-Induced Emission Active Materials for Sensing of Biologically Important Molecules and Drug Delivery System

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