Ailanthone Suppresses Liver Cancer Cell Malignant Behavior by Regulating microRNA-489-3p
Ruiyu Guan,
Yiyang Yao,
Zengliang Liang
Abstract:Previous literature has validated the clinical effectiveness of ailanthone in repressing the development of different human cancers. Therefore, this project aimed to investigate the role and possible mechanism of ailanthone in liver cancer. Huh-7 cells were treated with various concentrations of ailanthone (low-dose ailanthone, mediumdose ailanthone, high-dose ailanthone), or transfected with microRNA-negative control and microRNA-489-3p mimics. Furthermore, transfected Huh-7 cells were exposed with high-dose … Show more
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