Air-brush spray coated Ti3C2-MXene-graphene nanohybrid thin film based electrochemical biosensor for cancer biomarker detection

Multimodal Biosensing of Foodborne Pathogens

“…For example, MXene-graphene nanohybrid thin film, fabricated through air-brush spray coating, serves as an efficient electrochemical biosensor for the identification of biomarkers. The integration of MXene and graphene enhances sensitivity, offering a promising platform for accurate biomarker detection [ 40 ]. GNP-adapted reduced graphene oxide nanosheets function as a dual-quencher system, enabling extremely sensitive recognition of carcinoembryonic antigens.…”

Disposable paper-based screen-printed electrochemical immunoplatform for dual detection of esophageal cancer biomarkers in patients' serum samples

“…In comparison to conventional methods for the detection of CB, electrochemical biosensors are preferred due to their relatively high sensitivity, enhanced specificity, the possibility of miniaturization, ease of operation, rapid response, moderate cost, non-invasive detection methods for biomolecules, and being readily quantifiable. 22–25 Many researchers have used different bioreceptors for fabricating biosensors, like aptamers, antibodies, 26,27 proteins, mircoRNA, 28,29 etc. , for cancer determination.…”

l-Cysteine functionalized magnetite nanoparticle adorned Ti3C2-MXene nanohybrid based screen printed immunosensor for oral cancer biomarker detection

“…13 Given their capability to provide indepth insights into early-stage cancer development and metastasis, biomarkers have been integrated with multiple biosensing platforms toward ultrasensitive cancer diagnostics. [14][15][16] Among them, electrochemical biosensors have emerged as a prominent approach owing to their low instrumentation costs, simple operation, miniaturization potential, real-time and rapid detection capabilities, and low sample requirements. 9,17 Additionally, the utilization of nanomaterials in biosensor development holds promise for enhancing sensitivity, response time, and specicity due to their exceptional conductive and catalytic characteristics, as well as ease of surface functionalization 18,19 A diverse array of two-dimensional (2D) materials have shown enticing interest over the last decade for the development of efficient biosensing platforms.…”

“…Therefore, the fabrication of nanohybrids by incorporating functional nanomaterials with Ti 3 C 2 -MXene becomes essential to prevent their self-restacking and to further enhance their electrochemical attributes. 14,31 Recently, transition metal nanomaterials have been commonly employed to increase the electroactive surface area and electron transport efficiency in electrochemical biosensors. 32 Furthermore, MXene nanosheets integrated with metal nanomaterials offer enhanced electrochemical properties, favourable biocompatibility, and improved conductivity, thereby extending their potential uses for developing electrochemical biosensing platforms.…”

“…Therefore, the fabrication of nanohybrids by incorporating functional nanomaterials with Ti 3 C 2 -MXene becomes essential to prevent their self-restacking and to further enhance their electrochemical attributes. 14,31…”