Air-jet spun PHBV/PCL blend tissue engineering scaffolds exhibit improved mechanical properties and cell proliferation

Kalva, Sumama Nuthana; Dalvi, Yogesh B.; P, Noorunnisa Khanam; Varghese, Ruby; Ahammed, Imran; Augustine, Robin; Hasan, Anwarul

doi:10.1016/j.rinma.2023.100415

Cited by 5 publications

(3 citation statements)

References 33 publications

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“…The medical field has also found various uses for PHBV. For example, it can be used to make biocompatible scaffolds [113,114] or slowly release drugs like insulin [115] or drugs for treating tumors [116]. Each of the monomers of PHBV is synthesized in a different metabolic pathway.…”

Section: Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (Phbv)mentioning

confidence: 99%

Genetic Modifications in Bacteria for the Degradation of Synthetic Polymers: A Review

Martín-González,

de la Fuente Tagarro,

De Lucas

et al. 2024

IJMS

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Synthetic polymers, commonly known as plastics, are currently present in all aspects of our lives. Although they are useful, they present the problem of what to do with them after their lifespan. There are currently mechanical and chemical methods to treat plastics, but these are methods that, among other disadvantages, can be expensive in terms of energy or produce polluting gases. A more environmentally friendly alternative is recycling, although this practice is not widespread. Based on the practice of the so-called circular economy, many studies are focused on the biodegradation of these polymers by enzymes. Using enzymes is a harmless method that can also generate substances with high added value. Novel and enhanced plastic-degrading enzymes have been obtained by modifying the amino acid sequence of existing ones, especially on their active site, using a wide variety of genetic approaches. Currently, many studies focus on the common aim of achieving strains with greater hydrolytic activity toward a different range of plastic polymers. Although in most cases the depolymerization rate is improved, more research is required to develop effective biodegradation strategies for plastic recycling or upcycling. This review focuses on a compilation and discussion of the most important research outcomes carried out on microbial biotechnology to degrade and recycle plastics.

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Section: Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (Phbv)mentioning

confidence: 99%

Genetic Modifications in Bacteria for the Degradation of Synthetic Polymers: A Review

Martín-González,

de la Fuente Tagarro,

De Lucas

et al. 2024

IJMS

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“…The blend of PCL and PHBV has been processed by various methods to tailor specific properties and applications. Kalva et al [111] employed air-jet spinning to fabricate PCL/PHBV submicron fibrous scaffolds. They evaluated the mechanical, morphological, and biological properties of the scaffolds created with different weight ratios of PHBV and PCL.…”

Section: Pcl/phbv Blendsmentioning

confidence: 99%

“…The addition of PCL to the blend improved the crystallinity, thermal stability, and mechanical properties of the PCL/PHBV scaffolds. Furthermore, Kalva et al [111] performed in vivo subcutaneous implantation studies to evaluate the compatibility of the blend with animal tissues. The results were promising with rats, as they remained generally healthy throughout the implantation period, and no significant adverse effects were observed on the implanted scaffolds.…”

Section: Pcl/phbv Blendsmentioning

confidence: 99%

Copolymers and Blends Based on 3-Hydroxybutyrate and 3-Hydroxyvalerate Units

Jin,

del Valle,

Puiggalí

2023

IJMS

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This review presents a comprehensive update of the biopolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), emphasizing its production, properties, and applications. The overall biosynthesis pathway of PHBV is explored in detail, highlighting recent advances in production techniques. The inherent physicochemical properties of PHBV, along with its degradation behavior, are discussed in detail. This review also explores various blends and composites of PHBV, demonstrating their potential for a range of applications. Finally, the versatility of PHBV-based materials in multiple sectors is examined, emphasizing their increasing importance in the field of biodegradable polymers.

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Phase behavior-microstructure-crystallization kinetics correlations in semi-crystalline/amorphous PCL/SAN mixtures filled with nanosilica

Salkhi Khasraghi,

Khonakdar,

Hemmati

et al. 2024

Arabian Journal of Chemistry

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Air-jet spun PHBV/PCL blend tissue engineering scaffolds exhibit improved mechanical properties and cell proliferation

Cited by 5 publications

References 33 publications

Genetic Modifications in Bacteria for the Degradation of Synthetic Polymers: A Review

Genetic Modifications in Bacteria for the Degradation of Synthetic Polymers: A Review

Copolymers and Blends Based on 3-Hydroxybutyrate and 3-Hydroxyvalerate Units

Phase behavior-microstructure-crystallization kinetics correlations in semi-crystalline/amorphous PCL/SAN mixtures filled with nanosilica

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