“…Air pollution (outdoor and indoor) is a grave risk to human health that affects nearly everyone in the world and nearly every organ in the body (64). In addition to public health measures that encourage avoidance, compelling epidemiological studies and mechanistic studies will add to the body of evidence to persuade global policy change, particularly for vulnerable populations (47). The impact of air pollution goes far beyond the lung (COPD, lung cancer, poor lung development), additionally linked to cardiovascular deaths, stroke, bladder cancer, childhood leukemia, risk of dementia, diabetes mellitus prevalence, allergic rhinitis, allergic sensitization, autoimmunity, osteoporosis and fractures, conjunctivitis, dry eye disease, blepharitis, inflammatory bowel disease, increased intravascular coagulation, decreased glomerular filtration rate, atopic and urticarial skin disease, acne, and skin aging (62,63).…”