Airborne contact dermatitis from atranorin

Lorenzi, Sandra; Guerra, Liliana; Vezzani, Claudia; Vincenzi, Colombina

doi:10.1111/j.1600-0536.1995.tb00797.x

Cited by 13 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Atranorin is a para-β-orcinol depside bearing CO 2 Me, CHO and OH groups, frequently found in lichens, it seems that the wood of O. floribunda used in this study was contaminated. Among the aromatic lichen compounds, atranorin is the most frequent allergenic agent responsible for airborne contact dermatitis 21,22 .…”

Section: Resultsmentioning

confidence: 99%

Chemical constituents from Ouratea floribunda: complete¹H and 13C NMR assignments of atranorin and its new acetyl derivative

Carvalho¹,

Carvalho²,

Braz‐Filho³

2000

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

O fracionamento cromatográfico do extrato hexânico da madeira de Ouratea floribunda (Ochnaceae) forneceu, além dos triterpenos friedelina (1), friedelanol (2) e lupeol (3), o depsídeo atranorina (4). As estruturas das substâncias isoladas foram determinadas através da análise dos dados espectroscópicos de RMN 1 H e 13 C, massas e comparação com dados da literatura. A atribuição inequívoca dos deslocamentos químicos dos átomos de carbono e hidrogênio do depsídeo 4 e do seu novo derivado monoacetilado 4a foi realizada através de técnicas uni-e bidimensionais de RMN ( 1 H-1 H COSY e NOESY, 1 H-13 C HMBC e HMQC) e está sendo descrita pela primeira vez na literatura.Chromatographic fractionation of the hexane extract from the wood of Ouratea floribunda (Ochnaceae) afforded friedelin (1), friedelanol (2), lupeol (3) and the depside atranorin (4). The structure elucidation of the isolated compounds was performed by spectrometric analysis involving comparison with literature data. The unambiguous assignments of 1 H and 13 C NMR data of atranorin 4 and its acetyl derivative 4a are reported for the first time and involved 1 H-1 H homonuclear (COSY and NOESY) and 1 H-13 C heteronuclear (HMQC and HMBC) NMR experiments.

show abstract

Section: Resultsmentioning

confidence: 99%

Chemical constituents from Ouratea floribunda: complete¹H and 13C NMR assignments of atranorin and its new acetyl derivative

Carvalho¹,

Carvalho²,

Braz‐Filho³

2000

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

show abstract

“…Any part of the body may be in contact with fragranced cosmetics: scalp: shampoo, hair lacquer, hair gel (43,44); face: skin care products (8,44), aftershave (45), perfumed tissue handkerchiefs (24,46), airborne from perfumes on clothing ( 42, 4 7); the eyelids: eye cosmetics (48); the lips: lipstick, toothpaste (49,50); the neck: aftershave, perfume (39,47); the trunk: body lotion (51); the axillae: deodorant and antiperspirant (47,(52)(53)(54); the arms and legs: body lotion (55); the perianal area: fragranced(moistened) toilet tissue (25,27); the vulval area: feminine hygiene sprays (34,56), sanitary napkins (26,27), topical drugs (29); the hands: moisturizing creams ( 47), soap (57); and the feet: scented antiperspirants.…”

Section: Sites Of Contact With Fragrancesmentioning

confidence: 99%

“…It can be expected, however, that the neck, the skin behind the ear and the axillae (77) are often implicated, being exposed to products with high concentrations of fragrances (perfume, deodorant). Also, the sensitive skin of the face and the eyelids should be particularly susceptible to developing allergic contact dermatitis from fragrances in skin care produCts, decorative cosmetics and cleansing preparations, and from airborne contact dermatitis (39,40,41 ). Micro-trauma from shaving facilitates (photo) contact allergy to aftershave fragrances (70).…”

Section: Clinical Picture Of Allergic Contact Dermatitis From Fragrancesmentioning

confidence: 99%

Adverse reactions to fragrances

Groot¹,

1997

View full text Add to dashboard Cite

Con/act Dermatilis. /997. 36, This article reviews side-effects of fragrance materials present in cosmetics with emphasis on clinical aspects: epidemiology, types of adverse reactions, clinical picture, diagnostic procedures, and the sensitizers. Considering the ubiquitous occurrence of fragrance materials, the risk of sideeffects is small. In absolute numbers, however, fragrance allergy is common, affecting approximately 1% of the general population. Although a detailed profile of patients sensitized to fragrances needs to be elucidated, common features of contact allergy are: axillary dermatitis, dermatitis of the face (including the eyelids) and neck, well-circumscribed patches in areas of "dabbing-on" perfumes (wrists, behind the ears) and (aggravation of) hand eczema. Depending on the degree of sensitivity, the severity of dermatitis may range from mild to severe with dissemination and even erythroderma. Airborne or "connubial" contact dermatitis should always be suspected. Other less frequent adverse reactions to fragrances are photocontact dermatitis, immediate contact reactions and pigmentary changes. The fragrance mix, although very useful for the detection of sensitive patients, both causes false-positive and false-negative reactions, and detects only 70% of perfumeallergic patients. Therefore, future research should be directed at increasing the sensitivity and the specificity of the mix. Relevance is said to be established in 50-65% of positive reactions, but accurate criteria are needed. Suggestions are made for large-scale investigation of several fragrances on the basis of literature data and frequency of use in cosmetics. The literature on adverse reactions to balsam of Peru (an indicator for fragrance sensitivity), essential oils (which currently appear to be used more in aromatherapy than in perfumery) and on fragrances used as flavours and spices in foods and beverages is not discussed in detail, but pertinent side-effects data are tabulated and relevant literature is provided. Key words: perfume; fragrance; adverse reactions; fragrance mix; balsam of Peru; essential oils; allergic contact dermatitis; photosensitivity; immediate contact reactions; pigmented cosmetic dermatitis; occupational contact dermatitis. © Munksgaard, 1997. Accepted for publication 15 October 1996This article reviews side-effects of fragrance materials present in cosmetic products with emphasis on clinical aspects: epidemiology, types of adverse reactions, clinical picture, diagnostic procedures, and the sensitizers. Adverse reactions to balsam of Peru, a marker for fragrance sensitivity (!), which detects approximately 50% of patients allergic to fragrance materials (2), and to fragrances from non-cosmetic sources (e.g., flavours in food) are not discussed in detail. Essential oils seem to be more often used nowadays for medicinal (notably aromatherapy (3)) than for cosmetic purposes. Only the adverse reactions from their presence in cosmetic fragrances are included. However, because of their close relationship to fragr...

show abstract

Eichenmoos‐Extrakte [MAK Value Documentation in German language, 2004]

2012

The MAK‐Collection for Occupational Health and Safety

View full text Add to dashboard Cite

show abstract

Airborne contact dermatitis from atranorin

Cited by 13 publications

References 9 publications

Chemical constituents from Ouratea floribunda: complete¹H and 13C NMR assignments of atranorin and its new acetyl derivative

Chemical constituents from Ouratea floribunda: complete¹H and 13C NMR assignments of atranorin and its new acetyl derivative

Adverse reactions to fragrances

Eichenmoos‐Extrakte [MAK Value Documentation in German language, 2004]

Contact Info

Product

Resources

About