Airborne occupational contact dermatitis caused by extremely low concentrations of budesonide

Abstract

Menne T, Frosch P J, Lepoittevin J P (eds): Berlin, Springer, 2001: 787-815. 5. Frenk E, Kocsis M. Depigmentation dye to adhesive tape: ultrastructural comparison with vitiligo and vitiliginous depigmentation associated with a melanoma.A 52-year old installer of windows presented with a dyshidrotic and Fig. 1. A patch test positive to diethyl sebacate 5% pet. at day 7.

Airborne allergic contact dermatitis due to budesonide from professional exposure

“…A case of airborne allergic contact dermatitis in relatives of a patient treated with aerosols of budesonide is described in the recent literature (6). A single report of occupational airborne allergic contact dermatitis to budesonide is described in a nurse who administered the aerosolized drug and presented with eczematous areas on her face, neck, and upper limbs (7). As in our case, patch tests were positive for budesonide and hydrocortisone-17-butyrate.…”

Delayed hypersensitivity to corticosteroids in a series of 315 patients: clinical data and patch test results

“…Most patients were sensitized by the cutaneous route, which is in agreement with the literature (33). Airborne contact dermatitis (34, 35) and sensitization due to ‘by proxy’ (connubial or consort) dermatitis was also observed (results to be published in detail elsewhere). Patients who themselves administer inhalation corticosteroids, despite their wide use, rarely develop corticosteroid sensitization, and if it occurs, nasal seems to be more frequently involved than oral inhalation.…”

Patients with airborne sensitization/contact dermatitis from budesonide‐containing aerosols ‘by proxy’

“…Raison‐Peyron et al (19) were the first authors to describe connubial or consort contact dermatitis from an inhalation corticosteroid‐containing budesonide in the mother of a 3‐year old boy treated for asthma. Moreover, Ponten (20) and also more recently Corraza (21) reported on airborne contact dermatitis from occupational exposure to such aerosols, notwithstanding the extremely low concentrations involved (20).…”