Airborne Transmission of Chickenpox in a Hospital

Leclair, Jeanne M.; Zaia, John A.; Levin, Myron J.; Congdon, Richard G.; Goldmann, Donald A.

doi:10.1056/nejm198002213020807

Cited by 246 publications

(108 citation statements)

References 7 publications

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“…Infection with VZV usually occurs by an airborne route, with high infectivity resulting in a secondary attack rate of w90% in households with susceptible individuals [31]. Airborne spread in hospitals is also well documented [34]. Uncertainty exists as to whether the portal of entry is the conjunctiva, pharynx or lungs.…”

Section: Pathogenesismentioning

confidence: 99%

Varicella pneumonia in adults

Mohsen

McKendrick²

2003

Eur Respir J

145

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Varicella is a common contagious infection in childhood with increasing incidence in adults. Pneumonia, although rare, is the most serious complication that commonly affects adults. Over the last two decades there have been major advances in the understanding of Varicella infections, management and prevention. This review discusses the epidemiology, pathogenesis, pulmonary manifestation, morbidity, longterm clinical consequences and current state of management of Varicella pneumonia in adults. Prevention and other disease-modifying therapy are also discussed.

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Section: Pathogenesismentioning

confidence: 99%

Varicella pneumonia in adults

Mohsen

McKendrick²

2003

Eur Respir J

145

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“…La varicelle est une maladie infantile très contagieuse qui survient tout au long de l'année et dont l'incidence augmente au cours des mois de mars, avril et mai [25]. L'homme est le seul réservoir connu du VZV et la transmission se fait par contact direct avec les lésions cutanées ou par voie respiratoire [26]. Cette transmission est suivie d'une réplication virale dans les ganglions lymphatiques régionaux et les cellules du système réticulo-endothélial.…”

Section: Vaccin Contre Le Zona éPidémiologieunclassified

Prévention des infections à papillomavirus et du zona : nouveaux vaccins

Silbermann

Launay

2007

Med Sci (Paris)

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“…22 Importantly, nosocomial transmission of VZV to seronegative individuals who had no known contact with the index case-patient has occurred. [25][26][27][28] The roles of air ventilation systems and intermediaries who may have harbored clinical or subclinical infection (eg, hospital staff) are poorly understood.…”

Section: What Constitutes a Vzv Exposure Among Recipients Of Hematopomentioning

confidence: 99%