Airflow limitation among workers in a labour-intensive coal mine in Tanzania

Mamuya, Simon; Bråtveit, Magne; Mashalla, Yohana; Moen, Bente E.

doi:10.1007/s00420-006-0167-7

Cited by 8 publications

(7 citation statements)

References 26 publications

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“…al. also reported that exposure to coal mine dust was associated with airway limitation as measured by FEV 1 /FVC and the predicted FEV 1 (%) [29]. By comparing the three groups of miners in the present study, our lung ventilation function data provide further evidence that airway dysfunction may be a predominant feature in the initial development and progression of the lung disease associated with coal mining.…”

Section: Discussionsupporting

confidence: 71%

Alterations of serum biomarkers associated with lung ventilation function impairment in coal Workers: A cross-sectional study

Ji-min¹,

Carroll

Liang

et al. 2011

Environ Health

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BackgroundPrevious studies have demonstrated that alterations in certain circulating biomarkers may be correlated with Coal workers' pneumoconiosis (CWP). This study investigated the relationship between changes of serum biomarkers and pulmonary function during the development of CWP.MethodsLung function parameters and specific serum indices were measured in 69 non-smoking coal workers, including 34 miners with CWP, 24 asymptomatic miners and 11 miners with minimal symptoms. The associations between changes in pulmonary function and serum indices were tested with Pearson's correlation coefficients. Multivariable analysis was used to estimate the predictive power of potential determinant variables for lung function.ResultsCompared to healthy miners, lung function (FVC, FEV1, FEF50, FEF75, FEF25-75 % of predicted values) was decreased in miners with CWP (p < 0.05). Increased serum matrix metalloproteinase-9 (MMP-9) was associated with decreased FVC% of predicted values in the asymptomatic miners (r = -0.503, p = 0.014).ConclusionsIn coal mine workers, alterations of lung function parameters are associated with the development of CWP and with changes in circulating MMP-9, TIMP-9, IL-13 and IL-18R. These serum biomarkers may likely reflect the pathogenesis and progression of CWP in coal workers, and may provide for the importance of serum indicators in the early diagnosis of lung function injury in coal miners.

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Section: Discussionsupporting

confidence: 71%

Alterations of serum biomarkers associated with lung ventilation function impairment in coal Workers: A cross-sectional study

Ji-min¹,

Carroll

Liang

et al. 2011

Environ Health

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“…Our data showed that the majority of CWP patients were tunneling and coal mining workers. In general, tunneling and mining miners had highest levels of dust exposure and the highest risk for CWP [ 13 , 14 ]. The highest numbers of patients with the higher stages corresponded to the tunneling and mining miners.…”

Section: Discussionmentioning

confidence: 99%

Prevalence Characteristics of Coal Workers’ Pneumoconiosis (CWP) in a State-Owned Mine in Eastern China

Han

et al. 2015

IJERPH

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Coal Workers’ Pneumoconiosis (CWP) is the primary occupational disease in China. However, information about the definite prevalence of CWP is only partially available. The aims of our study were to assess the prevalence characteristics of CWP in a state-owned coal mine, evaluate the effects of control measures and develop further preventive strategies for CWP. The total study population included 495 cases who were diagnosed with CWP from the construction of this coal mine to the end of October 2014. Individuals’ information, including duration of dust exposure, job titles, age as first diagnosis, stages of CWP, CWP progress, complications with pulmonary tuberculosis, death and others were collected and analyzed. The results showed that 71.11% of 495 CWP cases were stage I and 90.71% were involved in tunneling or coal mining. The mean dust exposure period in CWP patients was 26.7 years, the mean latent period was 29.3 years and the mean diagnosed age was 50.3 years old. The proportion of CWP diagnosed after ending dust exposure were remarkably increased with the time passing. Among the CWP cases, 36 (7.27%) were complicated with pulmonary tuberculosis. The mortality of patients with stage III was the highest (60.71%) (p < 0.0001). Our data obviously show that more strict policies to protect coal miners are needed to be implemented in China, especially for tunneling and mining workers.

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“…For current smokers, the amount of cigarette packets smoked in a year was calculated by multiplying numbers of cigarettes smoked per day times duration of smoking in days divided by 20. Never smokers were defined as individuals who had never smoked [14]. Questions on other pulmonary diseases which might have confounded the results were elicited.…”

Section: Respiratory Health Questionnairementioning

confidence: 99%

Dust Exposure, Fractional Exhaled Nitric Oxide and Respiratory Symptoms among Volcanic Rock Miners in Kilimanjaro, Tanzania

Mamuya

Sakwari

Ngowi

et al. 2018

Annals of Global Health

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Volcanic rock for use as building material is mined extensively in the North Eastern Region of Tanzania. Dust emitted from the rock may contain harmful elements such as crystalline silica, arsenic (As), cobalt (Co), boron (B) and mercury (Hg) which might contribute to severity and onset of health symptoms.Objective:This study assessed respiratory symptoms and fractional exhaled nitric oxide as a marker for respiratory inflammation in relation to dust exposure among workers in different job sections in volcanic block mining.Materials and Methods:A cross- sectional study assessed a total of 135 workers in which 70 were exposed and 65 none exposed. The mining activities are mainly manual, and include cutting of blocks underground, transporting blocks to the shaping area, shaping blocks, loading blocks and aggregates (Murom) to vehicles and clearing or expanding the site. Respiratory health questionnaires were administered through face–to-face interviews. A total of 28 samples of “total” dust were collected around the breathing zone of the workers using SKC Sidekick pump (model 224–50) with a flow rate of 2.0 l/min. FENO assessed respiratory system inflammation using a portable electrochemistry-based sensor (NIOX MINO).Findings:The overall arithmetic mean concentration of personal total dust exposure among the workers was 4.37 mg/m3 (range 0.15-20.84). The prevalence of acute cough and red eyes were significantly higher among exposed than among non exposed (35% vs 10% and 45% vs 14%, respectively). The ANOVA Boniferroni test showed a significant difference in mean FENO between stone cutters and none exposed (P = 0.005).Conclusions:This study suggests the strong association between working as a stone cutting and shaping with respiratory inflammation. There is a need for respiratory mask type P2 use to protect workers from the exposure. There is also need for the follow up study involving cohorts of all workers happened to be in the mine.

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Airflow limitation among workers in a labour-intensive coal mine in Tanzania

Abstract: Exposure to respirable coal mine dust was associated with airway limitation as measured by FEV(1)/FVC and predicted FEV(1)%.

Cited by 8 publications

References 26 publications

Alterations of serum biomarkers associated with lung ventilation function impairment in coal Workers: A cross-sectional study

Alterations of serum biomarkers associated with lung ventilation function impairment in coal Workers: A cross-sectional study

Prevalence Characteristics of Coal Workers’ Pneumoconiosis (CWP) in a State-Owned Mine in Eastern China

Dust Exposure, Fractional Exhaled Nitric Oxide and Respiratory Symptoms among Volcanic Rock Miners in Kilimanjaro, Tanzania

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