“…Based on the few reported cases, airplane ascent-and descent-triggered headache is characterized by sudden onset, severe, mainly unilateral pain localized to the orbital, temporal, frontal, sometimes parietal and facial regions; the symptoms rarely last more than 1 h, and the pain is jabbing, stabbing, shooting, bursting, pressing, piercing and sharp in quality (1)(2)(3)(4)(5)(6). Additional symptoms are rare, although unilateral tearing, nasal congestion and stuffy feeling of the face may be present (2)(3)(4). Physical examination, routine blood tests and head imaging studies are not specific (1)(2)(3)(4)(5)(6).…”