Airway complications after lung transplantation: a review of 151 anastomoses

Álvarez, Antonio; Algar, Javier Algar; Santos, Francisco; Lama, R.; Aranda, José Luis; Baamonde, C.; López-Pujol, Javier; Salvatierra, A.

doi:10.1016/s1010-7940(01)00619-4

Cited by 126 publications

(97 citation statements)

References 23 publications

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“…Unfortunately, in our study we were not able to look up data on reperfusion edema for the whole cohort because of missing chest X-rays necessary to grade primary graft dysfunction conform the new ISHLT classification. In other studies [14,27,28] AC also resulted in longer intubation periods post-operatively. In our study, we also found a longer duration of mechanical ventilation in patients with AC although the difference did not reach statistical significance.…”

Section: Discussionmentioning

confidence: 73%

Risk factors for airway complications within the first year after lung transplantation

Wauwer

Raemdonck

Verleden

et al. 2007

European Journal of Cardio-Thoracic Surgery

146

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Objective: Lung transplantation (LTx) has enjoyed increasing success with better survival in recent years. Nevertheless, airway anastomotic complications (AC) are still a potential cause of early morbidity and mortality. In this retrospective cohort study we looked at possible predictors of AC within the first year after LTx. Methods: Between July 1991 and December 2004, 232 consecutive single (n = 102) and bilateral (n = 130) LTx were performed (142 males and 90 females; mean age: 48 years [range 15-66 years]). Indications for LTx were emphysema (n = 113), pulmonary fibrosis (n = 45), cystic fibrosis (n = 35), pulmonary hypertension (n = 10), sarcoidosis (n = 7) and miscellaneous (n = 22). Donor variables (age, gender, PaO 2 / FiO 2 , mechanical ventilation, ischemic time and preservation solution) and recipient variables (age, diagnosis, length, gender, pre-operative steroids, smoking, cytomegalovirus matching, LTx type, anastomotic type, wrapping and bypass) were evaluated in an univariate and multivariate model. Results: Fifty-seven complications occurred in 362 airway anastomoses (15.7%) of which 55 (15.2%) within the first year after transplantation. Six patients died as a result of AC (mortality 2.6%) during the first year after LTx. In a univariate analysis (321 airway anastomoses at risk), anastomotic type (

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Section: Discussionmentioning

confidence: 73%

Risk factors for airway complications within the first year after lung transplantation

Wauwer

Raemdonck

Verleden

et al. 2007

European Journal of Cardio-Thoracic Surgery

146

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“…Bronchial ischemia is reported to be a significant risk factor for the development of airway complications [9]. The viability of the donor bronchus is initially dependent upon retrograde low-pressure collaterals derived from the pulmonary artery as bronchial arterial circulation is lost during the harvest of the donor lungs [3].…”

Section: Discussionmentioning

confidence: 99%

“…Reflecting these changes, the contemporary rate of anastomotic lesions following LuTx has dropped from 80% before 1983 [15] to 2.6-23.8% [6][7][8][9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Airway complications after lung transplantation: risk factors, prevention and outcome☆

Weder

İnci

Korom

et al. 2009

European Journal of Cardio-Thoracic Surgery

113

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“…Improvements in surgical techniques, immunosuppressive regimen, and postoperative care have resulted in markedly improved clinical outcomes, as airway complication rates have decreased, presently ranging from 5% to 30% with an associated mortality rate of 2%-3% [58][59][60][61][62][63].…”

Section: Bronchial Stenosis Following Lung Transplantation (Lt)mentioning

confidence: 99%

Silicone stents, the rigid bronchoscope, and the standard of care in central airway stenosis

Dutau

Maldonado

Laroumagne

et al. 2012

Curr Respir Care Rep

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Central airway stenoses often represent a therapeutic challenge and require a multidisciplinary approach involving interventional pulmonologists and thoracic surgeons. While surgery is often the preferred definitive modality, advances in bronchoscopic techniques have led to substantial improvements in patient symptoms and longterm quality of life using minimally invasive techniques generally safe when performed by experienced proceduralists. Endobronchial laser therapy, cryotherapy, conventional electrocautery, or argon plasma coagulation and photodynamic therapy have been used successfully. A variety of stents, silicone or self-expandable (covered or non-covered metallic stents), have been used though little significant progress has been achieved since the description of the dedicated airway silicone stents first described by JeanFrancois Dumon in the 1980s. Rigid bronchoscopy remains the method of choice for the treatment of both benign and malignant central airway obstruction, but significant technological advances allow for effective treatments using the flexible bronchoscope. Metallic non-covered stents are generally not recommended, except in selected patients with poor short-term prognosis.

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Airway complications after lung transplantation: a review of 151 anastomoses

Cited by 126 publications

References 23 publications

Risk factors for airway complications within the first year after lung transplantation

Risk factors for airway complications within the first year after lung transplantation

Airway complications after lung transplantation: risk factors, prevention and outcome☆

Silicone stents, the rigid bronchoscope, and the standard of care in central airway stenosis

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