Airway performance in infants with congenital tracheal stenosis associated with unilateral pulmonary agenesis: effect of tracheal shape on energy flux

Kageyama, Shiori; Takeishi, Naoki; Harada, Naoki; Taniguchi, Kao; Morita, Keiichi; Wada, Shigeo

doi:10.1007/s11517-022-02601-4

Cited by 2 publications

(4 citation statements)

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“…In this study, a realizable k - ε turbulence model [ 32 ] was implemented to simulate the turbulence mean flow field. This model was successfully applied to steady inhalation in a simulation of tracheal flow in a human airway [ 13 , 16 , 37 ]. The CFD software Simcenter STAR-CCM + 2020.2 (Siemens Digital Industries Software Inc., Plano, TX) was used for mesh generation and to solve the Navier–Stokes equations.…”

Section: Methodsmentioning

confidence: 99%

“…Along with the aforementioned clinical studies, recent theoretical and computational approaches have successfully been used to investigate aspects of pulmonary dynamics such as stresses and deformation [ 29 , 31 ], as well as the fully turbulent nature of tracheal flow during inhalation [ 5 , 13 , 14 , 30 , 37 , 42 ]. For instance, Brouns et al (2007) systematically investigated how pressure drop affected tracheal stenosis in the range between 50 and 90% and showed that the pressure drop over the normal glottis (~ 40% constriction) was negligible with respect to that induced by constrictions greater than 70%, which impaired breathing [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

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Fluid dynamic assessment of positive end-expiratory pressure in a tracheostomy tube connector during respiration

Kageyama

Takeishi

Taenaka

et al. 2022

Med Biol Eng Comput

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High-flow oxygen therapy using a tracheostomy tube is a promising clinical approach to reduce the work of breathing in tracheostomized patients. Positive end-expiratory pressure (PEEP) is usually applied during oxygen inflow to improve oxygenation by preventing end-expiratory lung collapse. However, much is still unknown about the geometrical effects of PEEP, especially regarding tracheostomy tube connectors (or adapters). Quantifying the degree of end-expiratory pressure (EEP) that takes patient-specific spirometry into account would be useful in this regard, but no such framework has been established yet. Thus, a platform to assess PEEP under respiration was developed, wherein three-dimensional simulation of airflow in a tracheostomy tube connector is coupled with a lumped lung model. The numerical model successfully reflected the magnitude of EEP measured experimentally using a lung phantom. Numerical simulations were further performed to quantify the effects of geometrical parameters on PEEP, such as inlet angles and rate of stenosis in the connector. Although sharp inlet angles increased the magnitude of EEP, they cannot be expected to achieve clinically reasonable PEEP. On the other hand, geometrical constriction in the connector can potentially result in PEEP as obtained with conventional nasal cannulae. Graphical abstract

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fluid dynamic assessment of positive end-expiratory pressure in a tracheostomy tube connector during respiration

Kageyama

Takeishi

Taenaka

et al. 2022

Med Biol Eng Comput

Self Cite

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“…Second, mediastinal distortion causes deviation of the trachea and an increase of the tracheal curvature 2 . A severely curved trachea aggravates airway resistance 3 . Aortopexy can relieve direct tracheal compression by the aorta.…”

Section: Figurementioning

confidence: 99%

“…2 A severely curved trachea aggravates airway resistance. 3 Aortopexy can relieve direct tracheal compression by the aorta. Furthermore, although there are reports of simple aortopexy being performed, 4,5 we included pericardiopexy as it can restore the mediastinum to the mid-line and correct excessive tracheal curvature.…”

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confidence: 99%