Aktivitas Biofungisida Ekstrak Daun Dewandaru (Eugenia uniflora L.) dalam Menghambat Pertumbuhan Fusarium sp. Secara In Vitro

Dewantari, Sasi Shania; Rahayu, Yuni Sri

doi:10.26740/lenterabio.v10n2.p199-206

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…The results of this study confirmed that bitter melon has the ability to inhibit fungal growth, as in previous studies, that bitter melon extract inhibited the growth of the fungus Fusarium oxysporum. 17 The antifungal test of the bitter melon extract was also effective against the growth of the fungus Candida albicans. The MIC was obtained at a concentration of 40%.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study

Pangesty,

Kurniati,

Ratnaningrum

2023

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Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections. Bitter melon contains various compounds that have potential to be used as antifungals, including flavonoids and saponins. The aim of this study was to determine the effect of bitter melon extract (Momordica charantia L) on the growth of Trichopyton rubrum. This study used bitter melon extract at concentrations of 5%, 25%, 50%, 75% and 100%. Ketoconazole concentrations of 2% was used as a positive control. Pure cultures of Trichopyton rubrum were diluted using physiological NaCl. Fungal growth was observed microscopically and macroscopically. Results showed that Trichopyton rubrum grew at a concentration of 5% while at concentrations of 25%, 50%, 75% and 100% there was no Trichopyton rubrum growth. Bitter melon extract at a concentration of 25% had similar effect as ketoconazole 2%. Conclusion Bitter melon extract at concentrations of 25%, 50%, 75% and 100% had a similar effect to 2% ketoconazole in inhibiting the growth of Tricophyton rubrum.

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Section: Discussionmentioning

confidence: 99%

Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study

Pangesty,

Kurniati,

Ratnaningrum

2023

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“…to HEBC (human buccal epithelial cells) and CSH (cell surface hydrophobicity) and it is able to reduce biofilm formation for biofilm producing strains. 12 Other Research by Dewantari and Rahayu regarding the potential of Dewandaru leaf extract for antifungal activity states that Dewandaru leaf extract has the ability to inhibit the growth of Fusarium sp 13 .…”

Section: Discussionmentioning

confidence: 99%

Antifungal activity test of Dewandaru leaf extract (Eugenia uniflora L) against Candida in otomycosis

Wayan Lolik Lesmana,

Ni Putu Oktaviani Rinika Pranitasari,

I Gusti Ayu Mahaprani Danastri

et al. 2024

GSC Adv. Res. Rev.

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Background: Tropical climate conditions and a lack of public awareness about maintaining environmental cleanliness mean that infectious diseases are still a major health problem in Indonesia. Bacteria, viruses, fungi and parasites are pathogenic organisms that cause infections. Fungal infections receive less attention because they are rarely fatal for the sufferer. Fungal infections in the ear, known as otomycosis, are often caused by Candida fungi. The Dewandaru plant (E. uniflora L) as a type of plant that is widely used for traditional medicine in the community is known to have antifungal potential. This plant contains flavonoids, alkaloids, terpenoids, anthraquinones and tannins which have antifungal properties. Method: The method used in this research was experimental research with a post test only control group design on C. albicans test material. The positive control was 1% Clotrimazole suspension and the negative control was 96% ethanol solution. Result: Research showed that there was an inhibitory effect of E. uniflora L leaf extract in concentrations of 100%, 90% and 80% against the Candida albicans fungus. Average diameter of the inhibitory area of leaf extract E. uniflora L concentrations of 100%, 90% and 80% respectively were 22.2 mm; 19.0mm; and 18.0 mm, while the average diameter of the 1% Clotrimazole inhibition area was 31.8 mm. Conclusion: There is an inhibitory effect of Dewandaru leaf extract (E. uniflora L) in concentrations of 100%, 90% and 80% against the Candida albicans fungus.

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Aktivitas Biofungisida Ekstrak Daun Dewandaru (Eugenia uniflora L.) dalam Menghambat Pertumbuhan Fusarium sp. Secara In Vitro

Cited by 2 publications

References 20 publications

Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study

Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study

Antifungal activity test of Dewandaru leaf extract (Eugenia uniflora L) against Candida in otomycosis

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