Aktivitas Polifenol Teh Hijau (Camellia sinensis (L) O. Kuntze) Sebagai Imunomodulator melalui Respons Supresi Imunoglobulin E (IgE) pada Rinitis Alergika

Yusni, Yusni; R, Teuku Husni T.; Achmad, Tri Hanggono

doi:10.15395/mkb.v47n3.596

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…In a human study, green tea polyphenol administration (2 × 350 mg/day, for 14 days) has been reported to decrease the level of IgE in patients with allergic rhinitis compared with those in the control group, though not statistically significant [104]. Since evidence is limited, more clinical trials are warrant in this field to further elucidate the immuno-regulative activity of tea extracts and its components.…”

Section: Immuno-regulative Activity In Humansmentioning

confidence: 99%

Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review

Tang

Meng

Gan

et al. 2019

IJMS

270

150

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Tea is widely consumed all over the world. Generally, tea is divided into six categories: White, green, yellow, oolong, black, and dark teas, based on the fermentation degree. Tea contains abundant phytochemicals, such as polyphenols, pigments, polysaccharides, alkaloids, free amino acids, and saponins. However, the bioavailability of tea phytochemicals is relatively low. Thus, some novel technologies like nanotechnology have been developed to improve the bioavailability of tea bioactive components and consequently enhance the bioactivity. So far, many studies have demonstrated that tea shows various health functions, such as antioxidant, anti-inflammatory, immuno-regulatory, anticancer, cardiovascular-protective, anti-diabetic, anti-obesity, and hepato-protective effects. Moreover, it is also considered that drinking tea is safe to humans, since reports about the severe adverse effects of tea consumption are rare. In order to provide a better understanding of tea and its health potential, this review summarizes and discusses recent literature on the bioactive components, bioavailability, health functions, and safety issues of tea, with special attention paid to the related molecular mechanisms of tea health functions.

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Section: Immuno-regulative Activity In Humansmentioning

confidence: 99%

Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review

Tang

Meng

Gan

et al. 2019

IJMS

270

150

View full text Add to dashboard Cite

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“…przez 14 dni podawano badanym polifenole z zielonej herbaty dwa razy 350 mg na dobę i wykazano, że taka dawka obniża poziom IgE u pacjentów z alergicznym zapaleniem błony śluzowej nosa w porównaniu z pacjentami z grupy kontrolnej, jednak nie są to dane statystycznie istotne. [16] Należy więc przeprowadzić więcej badań, by wyjaśnić działanie immunoregulacyjne herbaty.…”

Section: Wykres 3 Preferencje Spożywania Rodzajów Herbaty W Codzienne...unclassified

Benefits and disadvantages of drinking different types of tea – awareness of people based on anonymous surveys

Grużewska-Piotrowska,

Pająk,

Hubka

et al. 2023

J Educ Health Sport

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Introduction: Tea comes from ancient China and it is obtained from the leaves of the plant known as Camellia sinensis. It can be distinguished six categories of the tea: white, green, yellow, black, oolong, pu-erh (dark, fermented) depending on the complex production processes. Tea contains various bioactive ingredients that have beneficial effects on health. In addition, tea drinking is considered safe for humans as severe side effects from ingestion of tea infusion or extract are rarely observed. The aim of the study: The aim of the study was to assess the level of knowledge among people about bioactive ingredients, different types of tea, health benefits, safety issues and disadvantages of drinking tea based on anonymous surveys. Materials and methods: The research material was collected using an anonymous survey in June 2023. The obtained results were analyzed and verified on the basis of scientific literature and statistically processed using Microsoft Office Excel. Discussion and conclusions: 97% of respondents drink tea, and 59.3% of people reach for it every day. The most commonly consumed type is green tea. 58.6% of respondents believe that tea may have health properties, and 80.9% believe that tea is not harmful to health. Tea contains numerous bioactive ingredients, including: polyphenols, polysaccharides, aminoacids, alkaloids, saponins, enzymes, minerals. They are responsible for a number of functions affecting human health, including: antioxidant, anti-inflammatory, immunoregulatory, anti-cancer, cardiovascular, anti-diabetic, anti-obesity and liver-protective properties. In tea, the bioavailability of active ingredients depends on the method of brewing, but also on the type of tea. Despite the many benefits, attention should be paid to the contamination of tea with heavy metals, pesticides and mycotoxins, and to excessive consumption of substances such as caffeine, as they can cause side effects observed in studies.

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“…8,10 Polyphenol has antioxidant levels 100 times more effective than vitamin C and 25 times more effective than vitamin E. In addition, polyphenol is also thought to have antiinflammatory and anti-allergic activities. 11 Based on experimental research studies on rats, the results show that in experimental group who were given ethanol and black tea had organ improvement compared to the group that was only given ethanol. Where in this research, the improvement of black tea was thought to be an activity of the antioxidant catechin.…”

Section: Issn: 2250-1177mentioning

confidence: 99%

THE The Effect of Green Tea Infusion (Camellia sinensis) on Histopathology of White Rat (Rattus norvegicus) Liver Sprague dawley Strain Induced by Ethanol

Muhartono¹,

Salsabila²,

Ayu³

2020

J. Drug Delivery Ther.

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Aims: This research aims to determine the effect of green tea infusion (Camellia sinensis) on the hitopathology of white rat liver induced by ethanol. Method: This study used 30 rats divided into 5 groups as follow negative control group (K1) given aquades, positive control group (K2) given 20% 2 mL/day peroral, treatment group 1, 2, 3 (P1, P2, P3) given 20% ethanol 2 mL/day peroral followed by green tea infusion with doses 0,375 g/day, 0,75 g/day, and 1,5 g/day single dose per oral for 14 days. The the liver of the rat is taken for microscopic examination. The mean Manja Roenigk scores obtained were K1=1,16, K2=3,36, P1=2,8, P2=2,68, and P3=2,56. Data were tested with the Kruskal-wallis test followed by Mann whitney’s post hoc test. Results: The results showed a significant mean difference between positive group (K2) and the treatment group P1, P2, and P3. There is no significant mean difference between P1-P2, P1-P3, and P2-P3 which means giving green tea infusion (Cameliia sinensis) in P2 and P3 gave almost the same effect as P1. Conclusion: There is an effect of giving green tea infusion (Camellia sinensis) to the histopathology of white rat liver induced by ethanol. Keywords: antioxidants, ethanol, green tea infusion, liver histopathology.

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Aktivitas Polifenol Teh Hijau (Camellia sinensis (L) O. Kuntze) Sebagai Imunomodulator melalui Respons Supresi Imunoglobulin E (IgE) pada Rinitis Alergika

Cited by 3 publications

References 9 publications

Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review

Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review

Benefits and disadvantages of drinking different types of tea – awareness of people based on anonymous surveys

THE The Effect of Green Tea Infusion (Camellia sinensis) on Histopathology of White Rat (Rattus norvegicus) Liver Sprague dawley Strain Induced by Ethanol

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