Akut Pulmoner Embolili Hastalarda R Dalga Pik Zamanının Tanısal Öngörücü Değeri

Abstract

This study aimed to investigate the diagnostic predictive value of R wave peak time (RWPT) in patients admitted to the emergency department with a preliminary diagnosis of acute pulmonary embolism (APE). Computerized tomographic pulmonary angiography (CTPA) was performed in 74 consecutive patients with suspected APE, and of these 66 patients with appropriate electrocardiogram (ECG) and CTPA images composed the study population.By using CTPA, APE was confirmed in 27 patients. While the atrial arrhythmia, right axis deviation, complete or incomplete right bundle branch block, prominent S wave in the lead DI, S1Q3T3 pattern, and RWPT in the lead DIII (40±11 vs. 31±13 ms) were statistically different in patients with APE compared to those without APE (p<0.05, for all), the other ECG findings were similar. Multivariate analysis revealed that RWPT in the lead DIII (odds ratio: 14.959, 95% confidence interval: 1.811-123.582, p=0.012) was found to be an independent predictor of APE. A receiver operating characteristic analysis was drawn to show the best cutoff value of the RWPT in the lead DIII to predict APE was ≥40 ms with 48.1% sensitivity and 87.2 % specificity (area under curve (AUC): 0.718; 95% CI: 0.593-0.843; p=0.003).The present study demonstrated that the RWPT in the lead DIII may have diagnostic predictive value for APE. In addition, it may be useful in electrocardiographic signs for the diagnosis of APE.

Effects of Zingiber officinale and Seeds of Aframomum melegueta Extract on Some Biochemical and Immunological Indices of Electric Foot Shock Stress-Induced Wistar Rats

“…Since the induction of electric foot shock has been implicated in the pathogenesis of inflammatory response, the ability of these extracts to cause a decrease in the cortisol level supports its antiinflammatory potentials. Karabağ et al [22] made similar assertions. The result showing the effect of ethanol extract of Z. officinale and A. melegueta on Urea and Creatinine concentration in electric-shock stress induced rats is presented in Table 1.…”

“…The determination of C-reactive protein was carried out using an essential reagent required for an immune enzyme metric assay which include high affinity and specificity antibodies (enzyme and immobilized) with different and distinct epitope recognition in excess and native antigen, as described [22].…”

Prognostic Value of Symptoms and Signs in Geriatric Acute Pulmonary Embolism—An Analytical Study

“…5 While embolism in the main pulmonary veins results in severe dyspnea, embolism in more distal veins may cause mild respiratory distress and cough. 6 7 Patients with risk factors for venous thromboembolism are also at risk of APE, but 30% of those with a diagnosis of APE are reported to have no risk factor. 8 In this study, we aimed to evaluate the relationship between APE symptoms and short-term mortality in patients presenting to the emergency department.…”