Abstract:Acute pancreatitis is potentially fatal. It can be diagnosed based on present history, clinical appearance, and typical findings from laboratory and radiologic investigations. All patients must be admitted to hospital, as the disease course cannot be predicted at initial presentation. Increasing severity demands increasingly individualized therapy. The most important interventions are fast fluid resuscitation and analgesic therapy with opioids. Therapeutic agents specific to pancreatitis have failed to show an… Show more
“…The role of antibiotic therapy and nutritional support in the therapeutic regimen has been profoundly reassessed during recent years. [6] Imipenem can be given for a duration of 10-14 days, if no systemic complications are present. In developing countries, the use of prophylactic antibiotics early on to the disease in selected cases can be beneficial as the cost of managing complications of pancreatitis can be a limiting factor for patients.…”
“…The role of antibiotic therapy and nutritional support in the therapeutic regimen has been profoundly reassessed during recent years. [6] Imipenem can be given for a duration of 10-14 days, if no systemic complications are present. In developing countries, the use of prophylactic antibiotics early on to the disease in selected cases can be beneficial as the cost of managing complications of pancreatitis can be a limiting factor for patients.…”
Our data reinforce that a step-up approach in patients with necrotizing pancreatitis is a feasible and safe treatment procedure. For the first time, we could demonstrate satisfactory results in a long-term follow-up including QOL.
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