Al³⁺‐Morpholine‐appended Anthracene Ensemble as a Dual Photonic Switch for H₂PO₄⁻ and CN⁻ Ions and its Biological Applications

Abstract

A highly selective Al 3+ -morpholine anthracene (1•Al 3+ ) chelate was designed as a novel fluorescent photonic switch for H 2 PO 4 − and CN − ions. The in situ-generated Al 3+ chelate could be used to detect H 2 PO 4 − ions only in the absence of CN − ions. In contrast, CN − ions effectively extruded Al 3+ from the chelate, resulting in the regeneration of probe 1 with a concomitant revival of PET, resulting in a turn-off response. By exploiting the complexation-and decomplexation-aided off-on switching system through the sequential addition of Al 3+ followed by H 2 PO 4 − or CN − , combinational photonic logic circuits, as well as image-guided fluorogenic tracking, was demonstrated.

A Comprehensive Review on Thiophene Based Chemosensors

“…The progress of selective optical signaling systems for ion detection is an emerging subject of interest in research from recent years due to the potentiality of such systems in analytical devices. Among the various available analytical tools for ion detection, fluorometric and colorimetric analysis are among the most important and most preferred optical tools that are used for the detection of various ions and molecules in a particular system due to their high selectivity, fast response, better sensitivity, real-time monitoring [ 1 ], and bioimaging capability [ 2 , 3 ].…”

An Acylhydrazone-Based Fluorescent Sensor for Sequential Recognition of Al3+ and H2PO4−

“…Dihydrogen phosphate (H 2 PO 4 − ) is an important component related to many intercellular activities, such as signaling mediation, protein phosphorylation, enzymatic reactions, ion-channel regulation, and so on [ 7 , 8 , 9 ]. However, excessive agricultural use of phosphate causes eutrophication or massive algal growth, leading to a deficiency in oxygen levels [ 10 , 11 , 12 ]. For these reasons, there has been a strong demand for the development of sensing and detection methods for Al 3+ and H 2 PO 4 − .…”

Bicarbonate Recognition Features of a Naphthobipyrrole‐strapped Calix[4]pyrrole

“…With our increasing understanding of various roles played by anions in natural systems including chemistry, biology, and the environment, the field of supramolecular chemistry concerned with anion recognition has drawn growing attention. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] In particular, bicarbonate (HCO 3 − ), a weakly basic anion, has become a specific target for recognition because of its heavy involvement in the maintenance of the pH homeostasis in biological and environmental systems. For instance, HCO 3 − is an essential element in physiological pH buffering systems and in signal transduction of intracellular events in the human body.…”