2021
DOI: 10.1101/2021.02.03.429530
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Albendazole reduces endoplasmic reticulum stress induced byEchinococcus multilocularisin mice

Abstract: Background Echinococcus multilocularis causes alveolar echinococcosis (AE), a rising zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to chemotherapy using benzimidazoles and surgical intervention, with relatively frequent disease recurrence in cases without radical surgery. Elucidating the molecular mechanisms underlying E. multilocularis infections and host-parasite interactions aids developing novel therapeutic options. This study explored an involvement of unfolde… Show more

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