1988
DOI: 10.1016/0378-5173(88)90072-5
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Albumin microspheres. III. Synthesis and characterization of microspheres containing adriamycin and magnetite

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Cited by 91 publications
(41 citation statements)
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“…The addition of further energy creates an emulsion of the magnetic particle sol in cottonseed (33), mineral (7), or vegetable oil (34). Depending upon composition and reaction conditions, addition of cross-linker and heat results in magnetic latex, 0.3 to 30 microns in average diameter, polydisperse in size, with up to 24 wt% magnetite (33). Theoretically, the insolubility of the polymer and magnetic particles in the oil continuum should guarantee uniform loading of magnetite per latex; however, no proof is provided.…”
Section: Introductionmentioning
confidence: 99%
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“…The addition of further energy creates an emulsion of the magnetic particle sol in cottonseed (33), mineral (7), or vegetable oil (34). Depending upon composition and reaction conditions, addition of cross-linker and heat results in magnetic latex, 0.3 to 30 microns in average diameter, polydisperse in size, with up to 24 wt% magnetite (33). Theoretically, the insolubility of the polymer and magnetic particles in the oil continuum should guarantee uniform loading of magnetite per latex; however, no proof is provided.…”
Section: Introductionmentioning
confidence: 99%
“…First, the application of mechanical energy creates a dispersion of magnetite in the presence of aqueous albumin (33), chitosan (7), or polyvinylalcohol (34) polymers. The addition of further energy creates an emulsion of the magnetic particle sol in cottonseed (33), mineral (7), or vegetable oil (34).…”
Section: Introductionmentioning
confidence: 99%
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“…Owing to their easy preparation, low fabrication cost, high chemical stability and unique electrical, optical, thermal, rheological, catalytic and magnetic properties, ferrites, either in the form of nanopowders or surface-stabilized nanoparticles suspended in a carrier liquid (ferrofluid) [3], have widespread use in electronics [4], magneto-optics [5], magnetocaloric refrigeration [6], dynamic sealing [7], high-density information storage [8], oscillation damping [9] and catalysis [10]. Among the nanocrystalline ferrites, Fe 3 O 4 and γ -Fe 2 O 3 have attracted particular interest as ideal candidates for different biomedical applications including enzyme encapsulation [11], biosensor design [12,13], cell labelling/separation [14] and oligonucleotide identification [15], magnetic resonance imaging (MRI) [16][17][18], tumour hyperthermia [19,20] and magneticallytargeted drug delivery [21][22][23][24] due to their dimensions being comparable to the cells and biomolecules, low toxicity and biocompatibility, high saturation magnetization values and their easy manipulation with low magnetic fields.…”
Section: Introductionmentioning
confidence: 99%
“…The enzymes have been immobilized on many kinds of support materials (Cao & Li, 1999), among them, the magnetic particles, which can be easily separated from the reaction system by applying a magnetic field, have aroused strong interests to manufacture enzyme-processed products in industry (Dekker, 1990;Kronick & Gilpin, 1986;Gupta, Hung, Lam, & Perrier, 1988;Mehta, Upadhyay, Charles, & Ramchand, 1997).…”
Section: Introductionmentioning
confidence: 99%