Alcohol &amp; Drug Abuse: Long-Acting Stimulants for the Treatment of Attention-Deficit Disorder in Cocaine-Dependent Adults

Castañeda, Ricardo; Levy, Robert; Hardy, Marcos; Trujillo, Manuel

doi:10.1176/appi.ps.51.2.169

Cited by 41 publications

(19 citation statements)

References 26 publications

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Section: Cocaïneunclassified

“…L'hypothèse d'une appétence sélective pour les substances psychostimulantes illicites chez les sujets TDAH a été envisagée [8,12]. D'après l'expérience clinique de Castaneda et al [8], certains sujets hyperactifs rapporteraient une réaction « paradoxale » à la cocaïne. Au lieu de ressentir une excitation et une exacerbation de leur symptomatologie psychiatrique, la cocaïne induirait chez eux des effets bénéfiques « paradoxaux » : relaxation, anxiolyse, stabilisation de l'humeur, amélioration de l'attention sélective, augmentation de la capacité à s'engager dans des activités productives et absence d'effets euphorisants.…”

Section: Cocaïneunclassified

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Le trouble déficit de l’attention-hyperactivité et ses relations avec les conduites addictives

Delavenne

Thibaut

2009

Psychiatr Sci Hum Neurosci

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Le trouble déficit de l'attention-hyperactivité (TDAH) peut être une comorbidité psychiatrique chez les usagers de substance. Cet article a pour but d'étudier le lien entre le TDAH et les addictions. Pour cela, nous décrirons le tableau clinique du TDAH chez l'adulte et la prévalence des addictions dans cette population. Nous aborderons ensuite les modèles explicatifs qui pourraient permettre de mieux comprendre la forte intrication du TDAH et des pratiques addictives. Enfin, nous évoquerons l'influence à long terme du traitement psychostimulant chez les enfants hyperactifs et les recommandations actuelles de prise en charge des usagers de substances souffrant d'un TDAH. Mots clés TDAH · Addiction · Troubles liés à l'usage de substances illicites · ComorbiditéAbstract Attention deficit hyperactivity disorder (ADHD) is a common psychiatric comorbidity in substance use disorders. The aim of this article is to review the link between ADHD and addictive disorders. For this purpose, we will describe the clinical symptomatology of ADHD in adults and the prevalence of addiction in this population. We will broach the explanatory models for this comorbidity. Finally, we will evoke the long-term consequences of psychostimulant treatment in children with ADHD and the current treatment recommendations for substance users suffering from ADHD.

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Section: Cocaïneunclassified

Le trouble déficit de l’attention-hyperactivité et ses relations avec les conduites addictives

Delavenne

Thibaut

2009

Psychiatr Sci Hum Neurosci

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“…A positive influence of ADHD pharmacotherapy on the course of SUDs has been recorded in case reports, but it has not yet been studied in a controlled manner (Castaneda, Levy, Hardy, & Trujillo, 2000;Levin, Evans, & Kleber, 1999;Somoza et al, 2004). With the exception of one placebo-controlled study among cocaine abusers (Schubiner et al, 2002), no effectiveness studies on pharmacotherapy in adults with SUD have been found in the literature.…”

Section: Pharmacotherapymentioning

confidence: 99%

An intervention program for ADHD in patients with substance use disorders: Preliminary results of a field trial

Goossensen¹,

Glind

Carpentier

et al. 2006

Journal of Substance Abuse Treatment

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“…Weekly individual relapse prevention therapy was also provided. Recent pilot studies also support that MPH might reduce cocaine use and ADHD symptoms [77]. However, these are open trials, and double blind controlled trials are clearly warranted.…”

Section: Pharmacotherapy Of Attention Deficit Hyperactivity Disorder mentioning

confidence: 99%

Attention deficit hyperactivity disorder (ADHD) and substance use disorders

Wilson

Levin

2001

Curr Psychiatry Rep

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Attention deficit hyperactivity disorder (ADHD) is a common childhood disorder that often continues to manifest symptoms into adulthood. In children and adults, this condition may contribute to addictive vulnerability. Several factors are common to the developmental psychopathology of these conditions, suggesting an underlying deficit in behavioral regulation as an explanation for this comorbidity. Developmentally, faulty learning processes or attempts to self-medicate dysfunctional behavior may contribute to the pathogenesis of substance use disorders. Substance abuse itself also may contribute to the development of attentional deficits and behavioral dysregulation through direct (eg, prenatal or self-inflicted exposures to neurotoxic substances) and indirect (eg, poverty, neglect, abuse) mechanisms. Because ADHD can be identified prior to the peak onset of substance use, effective treatment of this common disorder may reduce the development of substance use disorders. Adult ADHD may also contribute to the development and maintenance of substance use disorders Substance abuse patients may particularly benefit from treatment of this comorbidity.

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Alcohol & Drug Abuse: Long-Acting Stimulants for the Treatment of Attention-Deficit Disorder in Cocaine-Dependent Adults

Cited by 41 publications

References 26 publications

Le trouble déficit de l’attention-hyperactivité et ses relations avec les conduites addictives

Le trouble déficit de l’attention-hyperactivité et ses relations avec les conduites addictives

An intervention program for ADHD in patients with substance use disorders: Preliminary results of a field trial

Attention deficit hyperactivity disorder (ADHD) and substance use disorders

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