Alcohol and Atrial Fibrillation

Surma, Stanisław; Lip, Gregory Y.H.

doi:10.31083/j.rcm2403073

Cited by 3 publications

(2 citation statements)

References 62 publications

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“…Drinking RW or WW appears to be potentially safer than beer or spirits [119,120]. The dose of RW also seems to be relevant in influencing the risk of arrhythmia [121]. Consumption of two or more RW drinks per day was associated with a small but statistically significant increased AF risk [122].…”

Section: Discussionmentioning

confidence: 99%

“…There are no RCT that have evaluated the effect of RW on the risk of arrhythmia. Some cohort studies have suggested that RW, when consumed in moderation, may have a protective effect against atrial fibrillation [118], while others have found no significant effects or even potential harm [119][120][121]. A study published in the Journal of the American College of Cardiology [119] demonstrated a J-shaped relationship between total alcohol consumption and risk of AF in a population of middle-aged and older adults.…”

Section: Discussionmentioning

confidence: 99%

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Health Effects of Red Wine Consumption: A Narrative Review of an Issue That Still Deserves Debate

Lombardo¹,

Feraco

Camajani

et al. 2023

Nutrients

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A strong controversy persists regarding the effect of red wine (RW) consumption and health. Guidelines for the prevention of cardiovascular diseases (CVD) and cancers discourage alcohol consumption in any form, but several studies have demonstrated that low RW intake may have positive effects on CVD risk. This review evaluated randomised controlled trials (RCTs), examining the recent literature on the correlations between acute and chronic RW consumption and health. All RCTs published in English on PubMed from 1 January 2000 to 28 February 2023 were evaluated. Ninety-one RCTs were included in this review, seven of which had a duration of more than six months. We assessed the effect of RW on: (1) antioxidant status, (2) cardiovascular function, (3) coagulation pathway and platelet function, (4) endothelial function and arterial stiffness, (5) hypertension, (6) immune function and inflammation status, (7) lipid profile and homocysteine levels, (8) body composition, type 2 diabetes and glucose metabolism, and (9) gut microbiota and the gastrointestinal tract. RW consumption mostly results in improvements in antioxidant status, thrombosis and inflammation markers, lipid profile, and gut microbiota, with conflicting results on hypertension and cardiac function. Notably, beneficial effects were observed on oxidative stress, inflammation, and nephropathy markers, with a modest decrease in CVD risk in five out of seven studies that evaluated the effect of RW consumption. These studies were conducted mainly in patients with type 2 diabetes mellitus, and had a duration between six months and two years. Additional long-term RCTs are needed to confirm these benefits, and assess the potential risks associated with RW consumption.

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