Alcohol and Gastric Mucosa

Chey, William Y.

doi:10.1159/000197280

Cited by 41 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The increase in gastric calcium content can be explained in terms of gastric retention of test solution and also by an increase in gastric secretion of calcium as demonstrated by an increase in gastric 45Ca content after an intravenous 45Ca injection . Since acute intragastric administration of ethanol was reported to result in hemorrhagic erosion of the stomach and small intestine (13,14), the observed increase in gastric calcium secretion may have occurred secondarily to gastric mucosa damage.…”

Section: Discussionmentioning

confidence: 99%

Acute effect of ethanol on intestinal calcium transport.

Krishnamra

Boonpimol

1986

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Acute effect of ethanol on intestinal calcium transport.

Krishnamra

Boonpimol

1986

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

“…Most notably, alcohol, aspirin, and stress can cause erosions (Chey, 1972;Baskin et al, 1976;Morris, 1976, 1977;Garner, 1978). There are, however, differences in the apparent pathogenesis between F and these substances.…”

Section: Methodsmentioning

confidence: 99%

Studies of Human Gastric Mucosa After Application of 0.42% Fluoride Gel

et al. 1990

View full text Add to dashboard Cite

Dental prophylaxis with APF gels (1.23%) may cause gastric distress as a side-effect. This gastric irritation is probably due to a direct toxic effect of fluoride (F), swallowed in conjunction with the treatment, on the gastric mucosa. The aim of the present study was to investigate whether--and to what extent--a dental treatment with 3 g of a 0.42%-F gel could affect the gastric mucosa due to inadvertent swallowing of the gel. Ten subjects underwent a control gastroscopy, and two weeks later, a second gastroscopy was performed two h after a F gel treatment. During the gastroscopy, the mucosa was examined and the injuries graded according to an arbitrary scale. Four biopsies of the antral and corpus regions of the stomach were taken and evaluated histologically. The mean (+/- SD) amount of F retained after the application was 5.1 +/- 2.1 mg, i.e., 40% of the applied amount of F. Petechiae and erosions were found in the mucosa in seven of the ten patients. The histopathological evaluation revealed changes in nine of ten patients, with the surface epithelium as the most affected component of the mucosa. The present study clearly shows that a treatment with a F gel of rather low F concentration may result in injuries to the gastric mucosa. The importance of current recommended guidelines so that the amount of F swallowed during a gel application can be minimized is emphasized. From a toxicological standpoint, the use of a low-F gel instead of a 1.23%-F gel in small children is recommended for avoidance of adverse gastric effects.

show abstract

“…Therefore active agents and elements in tincures affect relatively quickly in spite of their small amount [4]. Polyphenolic active agents, as flavonoids, tannins, have antioxidant activities [30] and their presence in the extracts, e.g.…”

Section: Introductionmentioning

confidence: 99%

“…hesperidin in Tinctura Aurantii amari epicarpii et mesocarpii or tannins in Tinctura Ratanhiae, may be favourable in view of antioxidative value. Since volatile oils have relevant antioxidant activity it is supposed that the volatile oil containing tinctures also have antioxidant activities [4]. At the same time some trace elements, e.g.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant value and element content in some tinctures used in medication

Szentmihályi

Varga

Gergely

et al. 2015

Acta Biologica Hungarica

View full text Add to dashboard Cite

Tinctures are almost the oldest medicines and their use is substantial in the medication nowadays as well.The antioxidant values by ferric reducing/antioxidant power (FRAP) method and element content by inductively coupled plasma optical emission spectrometry (ICP-OES) were investigated in some tinctures official in the VII. and VIII. Pharmacopoeia Hungarica. The highest FRAP values were found for volatile oil containing Tinctura Aurantii amari epicarpii et mesocarpii, Tinctura Amara and Tinctura Valerianae (764.54 ± 19.90; 757.37 ± 14.46; 826.40 ± 5.89 µmol l -1 , respectively). The correlations between the FRAP values and dilution with different alcohol content in Tinctura Chinae, Tinctura Ipecacuanhae normata and Tinctura Strychni were also investigated. Remarkable differences were found between the element concentrations in the different tinctures. The element contents in tinctures are not so high in absolute values nevertheless the presence of essential selenium, zinc, manganese and copper is important since they have key role in the antioxidant system. The common feature of the tinctures seems to be the lithium content. The Ca to Mg concentration ratio was found to be shifted towards magnesium in some of the tinctures that can show a higher Mg absorption which could affect against the proinflammatoric processes in the cases of gastrointestinal diseases.

show abstract

Alcohol and Gastric Mucosa

Cited by 41 publications

References 15 publications

Acute effect of ethanol on intestinal calcium transport.

Acute effect of ethanol on intestinal calcium transport.

Studies of Human Gastric Mucosa After Application of 0.42% Fluoride Gel

Antioxidant value and element content in some tinctures used in medication

Contact Info

Product

Resources

About