“…Psychoactive substance use can have stronger effects on older adults since they are susceptible to age-associated physiological changes, and adverse effects from its use are particularly concerning for older adults living with chronic diseases ( Kuerbis, 2020 ). For example, binge drinking may be particularly dangerous for older adults due to an age-related increase in brain sensitivity to alcohol ( Van Skike & Matthews, 2021 ), and the addition of another psychoactive substance such as cannabis may add additional health risks ( Han & Moore, 2018 ; Subbaraman & Kerr, 2015 ). While an abundance of research has focused on the effects of cannabis and alcohol in the general population, there may be distinct risks associated with such use by older adults (e.g., cognitive decline) that are not well understood.…”