Alcohol and the digestive system – should it always be blamed?

Kasicka-Jonderko, Anna

doi:10.5114/pg.2012.32064

Cited by 5 publications

(4 citation statements)

References 89 publications

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“…Alcoholic beverages, especially red wine, probably have antibacterial activity against Helicobacter pylori and a protective effect against the ulcerogenic effect of ethanol on gastric mucosa. Flavonoids are responsible for these beneficial effects [ 64 ]. The consumption of 0.1 L of red wine has the potential to reduce the risk of gastric cancer.…”

Section: Red Wine Effects On Humans Organsmentioning

confidence: 99%

Contribution of Red Wine Consumption to Human Health Protection

et al. 2018

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Wine consumption has been popular worldwide for many centuries. Based on in vitro and in vivo studies, a certain amount of everyday wine consumption may prevent various chronic diseases. This is due, in part, to the presence and amount of important antioxidants in red wine, and, therefore, research has focused on them. Wine polyphenols, especially resveratrol, anthocyanins, and catechins, are the most effective wine antioxidants. Resveratrol is active in the prevention of cardiovascular diseases by neutralizing free oxygen radicals and reactive nitrogenous radicals; it penetrates the blood-brain barrier and, thus, protects the brain and nerve cells. It also reduces platelet aggregation and so counteracts the formation of blood clots or thrombi. The main aim of this review is to summarize the current findings about the positive influence of wine consumption on human organ function, chronic diseases, and the reduction of damage to the cardiovascular system.

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Section: Red Wine Effects On Humans Organsmentioning

confidence: 99%

Contribution of Red Wine Consumption to Human Health Protection

et al. 2018

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“…The negative effect of chronic ethanol consumption on the immune system and bone marrow has already been investigated. It is well established that the cells of the immune system of individuals affected by alcoholism have a lower capacity to migrate to the infectious site, phagocyte, and eliminate the pathogen, and the mechanism is often related to the production of cytokines and chemokines that have their levels and activities affected (21,(31)(32)(33)(34). In the bone marrow, studies have shown that alcohol consumption promotes important effects on hematopoiesis (35,36).…”

Section: Discussionmentioning

confidence: 99%

Chronic alcohol administration alters metabolomic profile of murine bone marrow

et al. 2023

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IntroductionPeople with hazardous alcohol use are more susceptible to viral, bacterial, and fungal infections due to the effect of alcohol on immune system cell function. Metabolized ethanol reduces NAD+ to NADH, affecting critical metabolic pathways. Here, our aim was to investigate whether alcohol is metabolized by bone marrow cells and if it impacts the metabolic pathways of leukocyte progenitor cells. This is said to lead to a qualitative and quantitative alteration of key metabolites which may be related to the immune response.MethodsWe addressed this aim by using C57BL/6 mice under chronic ethanol administration and evaluating the metabolomic profile of bone marrow total cells by gas chromatography–coupled mass spectrometry (GC–MS).ResultsWe identified 19 metabolites. Our data demonstrated that chronic ethanol administration alters the metabolomic profile in the bone marrow, resulting in a statistically diminished abundance of five metabolites in ethanol-treated animals: uracil, succinate, proline, nicotinamide, and tyrosine.DiscussionOur results demonstrate for the first time in the literature the effects of alcohol consumption on the metabolome content of hematopoietic tissue and open a wide range of further studies to investigate mechanisms by which alcohol compromises the cellular function of the immune system.

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“…A pleasure in itself, but actually only affirming the awaited taste sensation, is studying the wine list [ 27 ]. Traditionally most of the guests select lighter white wines to accompany dishes with a delicate flavour and dominant taste of umami, such as white fish or chicken in broth.…”

Section: Sweet and Umami Tastementioning

confidence: 99%

Pragmatically on the sense of taste – a short treatise based on culinary art

Waluga¹,

Jonderko²,

Buschhaus³

2013

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The sense of taste is essential for proper functioning of the organism. The authors describe, in an accessible way, the complex mechanisms of taste perception. The structure of particular taste receptors, variants of their activation, as well as physical and chemical factors modifying the sensation of taste, are presented. Exquisite culinary examples are given in order to facilitate the reader with the understanding of why, at the level of the cerebral cortex, a virtually infinite number of combinations of taste sensations can be perceived. The discourse is spiced up by reflections of the eminent philosopher of taste, J.A. Brillat-Savarin, who convinces us that food intake should be not only a physiological act, but also a refined pleasure.

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Alcohol and the digestive system – should it always be blamed?

Cited by 5 publications

References 89 publications

Contribution of Red Wine Consumption to Human Health Protection

Contribution of Red Wine Consumption to Human Health Protection

Chronic alcohol administration alters metabolomic profile of murine bone marrow

Pragmatically on the sense of taste – a short treatise based on culinary art

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