ABSTRACT. Objective: Research on moderate drinking has focused on the average level of drinking. Recently, however, investigators have begun to consider the role of the pattern of drinking, particularly heavy episodic drinking, in mortality. The present study examined the combined roles of average drinking level (moderate vs. high) and drinking pattern (regular vs. heavy episodic) in 20-year total mortality among late-life drinkers. Method: The sample comprised 1,121 adults ages 55-65 years. Alcohol consumption was assessed at baseline, and total mortality was indexed across 20 years. We used multiple logistic regression analyses controlling for a broad set of sociodemographic, behavioral, and health status covariates. Results: Among individuals whose high level of drinking placed them at risk, a heavy episodic drinking pattern did not increase mortality odds compared with a regular drinking pattern. Conversely, among individuals who engage in a moderate level of drinking, prior findings showed that a heavy episodic drinking pattern did increase mortality risk compared with a regular drinking pattern. Correspondingly, a high compared with a moderate drinking level increased mortality risk among individuals maintaining a regular drinking pattern, but not among individuals engaging in a heavy episodic drinking pattern, whose pattern of consumption had already placed them at risk. Conclusions: Findings highlight that low-risk drinking requires that older adults drink low to moderate average levels of alcohol and avoid heavy episodic drinking. Heavy episodic drinking is frequent among late-middle-aged and older adults and needs to be addressed along with average consumption in understanding the health risks of late-life drinkers. (J. Stud. Alcohol Drugs, 76, 552-558, 2015) Received: January 15, 2015. Revision: March 12, 2015. This work was supported by National Institute on Alcohol Abuse and Alcoholism Grant AA15685 and by Department of Veterans Affairs Health Services Research and Development Service funds. The opinions expressed here are the authors' and do not necessarily represent the opinions of the Department of Veterans Affairs. *Correspondence may be sent to Charles J. Holahan at the Department of Psychology (A8000), University of Texas at Austin, Austin, TX 78712, or via email at: holahan@utexas.edu. E XCESSIVE ALCOHOL CONSUMPTION is a major risk factor for chronic disease and injury (Rehm et al., 2009), but moderate alcohol consumption has been associated with reduced total mortality (Di Castelnuovo et al., 2006). However, research on moderate drinking has focused on the average level of drinking, masking diverse underlying patterns of drinking (Naimi et al., 2013). Among individuals whose average consumption is moderate, drinking may vary from a regular pattern to occasions of heavy episodic drinking. Recently, investigators have begun to consider the role of drinking pattern in mortality (Roerecke et al., 2011;Wannamethee, 2013).
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