Alcohol Consumption Patterns and Risk of Early-Onset Vasomotor Symptoms in Premenopausal Women

Kwon, Ria; Chang, Yoosoo; Kim, Yejin; Cho, Yoosun; Choi, Hyeon Ki; Lim, Gi Hyun; Kang, Jeonggyu; Kim, Kye Hyun; Kim, Hoon; Hong, Yun Soo; Park, Jihwan; Zhao, Di; Rampal, Sanjay; Cho, Juhee; Güallar, Eliseo; Park, Hyun-Young; Ryu, Seungho

doi:10.3390/nu14112276

Cited by 4 publications

(3 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Risk factors for hot flashes include menopausal status, smoking, alcohol consumption, low socioeconomic status, and high levels of stress [60][61][62]. The relationship between hot flashes and BMI is complicated by whether women are early in the menopausal transition (heavier women are more likely to have hot flashes) or later in the menopausal transition (leaner women are more likely to have hot flashes) [63].…”

Section: Covariatesmentioning

confidence: 99%

Frequency of Phytoestrogen Consumption and Symptoms at Midlife among Bangladeshis in Bangladesh and London

Sievert,

Sharmeen,

Begum

et al. 2023

Nutrients

View full text Add to dashboard Cite

There is a longstanding interest in the relationship between diet and hot flash symptoms during midlife, especially in whether phytoestrogens ease menopausal symptoms. The purpose of this study was to examine hot flashes, night sweats, trouble sleeping, and vaginal dryness in relation to the intake of foods rich in phytoestrogens among Bangladeshi women aged 35 to 59 years who were living either in Sylhet, Bangladesh (n = 157) or as migrants in London (n = 174). Consumption ranges for phytoestrogens were constructed from food frequencies. We hypothesized that diets rich in isoflavones, lignans, and coumestrol would be associated with lower symptom frequencies. However, adjusted logistic regression results showed that with each incremental increase in general phytoestrogen consumption (scale of 0 to 10), the likelihood of hot flashes increased by 1.4%. Each incremental increase in lignan consumption raised the likelihood of hot flashes by 1.6%. In contrast, the odds of vaginal dryness decreased by 2%, with each incremental increase in phytoestrogen and lignan consumption, and by 4%, with each incremental increase in isoflavone consumption. Night sweats and trouble sleeping were not associated with phytoestrogen intake in logistic regressions. Our findings add to the conflicting data on relationships between phytoestrogens and symptoms associated with menopause.

show abstract

Section: Covariatesmentioning

confidence: 99%

Frequency of Phytoestrogen Consumption and Symptoms at Midlife among Bangladeshis in Bangladesh and London

Sievert,

Sharmeen,

Begum

et al. 2023

Nutrients

View full text Add to dashboard Cite

show abstract

“…The relationship between alcohol consumption and the risk of vasomotor symptoms is controversial. Observational studies show mixed results and suggest that 1 unit of alcohol per day does not influence the occurrence of vasomotor symptoms (Avis et al, 2018;Kwon et al, 2022;Greendale and Gold, 2005). There are no data on the effect of alcohol cessation on vasomotor symptoms in women with (a history of) breast cancer.…”

Section: Alcohol Intakementioning

confidence: 99%

Clinical guidelines for managing menopausal symptoms in women with (a history of) breast cancer

Servayge,

Verduyn,

Page

et al. 2023

Facts Views Vis ObGyn

View full text Add to dashboard Cite

Background: One in eight women will be diagnosed with breast cancer. At the time of diagnosis, 75% of patients are postmenopausal. Many will receive anti-hormone therapy, which often induces menopausal symptoms. Premenopausal breast cancer patients frequently become postmenopausal as a result of the treatment and often experience menopausal symptoms. The increased incidence of breast cancer, combined with longer survival, has led to an increase in the number of women experiencing menopausal symptoms. Therefore, the management of menopausal symptoms in women with a history or current breast cancer is a relevant and common clinical problem. Objectives: To provide a clinically useful overview of the steps in the management of menopausal symptoms in women with (a history of) breast cancer. Materials and methods: A comprehensive literature review was conducted by authors JS and WT using the PubMed and Medline databases. Abstracts were critically appraised and, where appropriate, the full text was analysed. Main outcome measures: Not applicable. Results: Depending on the condition, either meta-analyses, randomised controlled trials or retrospective cohorts were identified. No evidence was found for some proposed treatments. Conclusions: Menopausal symptoms in women with (a history of) breast cancer require a patient-tailored approach. Shared decision making is paramount and adequate up-to-date knowledge can help the breast cancer specialist to advise and guide patients accordingly. What is new? A comprehensive, clinically-based overview of evidence-based treatment options for menopausal symptoms in women with (a history of) breast cancer.

show abstract

“…This study used baseline data from a longitudinal study of middle-aged Korean women designed to evaluate the changes in physical and psychological health status across menopausal stages among middle-aged Korean women. Thus, Korean women aged 42-52 years in the premenopausal stage and early transition of menopausal stage were recruited between 2014 and 2018 from the Kangbuk Samsung Health Study, a cohort study of Korean adults who underwent annual or biennial comprehensive health examinations at the Kangbuk Samsung Hospital Total Healthcare Centers in Seoul and Suwon, South Korea [14][15][16]. The eligibility criteria for enrolment included the following: (1) no hormone replacement therapy or history of hysterectomy or oophorectomy; (2) at least one menstrual period in the 3 months prior to the health screening examinations and no amenorrhea lasting for ≥60 days; and (3) no history of an underlying chronic disease (malignancy, renal failure, and hypo-/hyper-thyroidism) that may affect menstrual cycles.…”

Section: Study Populationmentioning

confidence: 99%

Nonalcoholic Fatty Liver Disease and Risk of Early-Onset Vasomotor Symptoms in Lean and Overweight Premenopausal Women

et al. 2022

Self Cite

View full text Add to dashboard Cite

The role of nonalcoholic fatty liver disease (NAFLD) in vasomotor symptom (VMS) risk in premenopausal women is unknown. We examined the prevalence of early-onset VMSs according to NAFLD status in lean and overweight premenopausal women. This cross-sectional study included 4242 premenopausal Korean women (mean age 45.4 years). VMSs (hot flashes and night sweats) were assessed using the Korean version of the Menopause-Specific Quality of Life questionnaire. Hepatic steatosis was determined using liver ultrasound; lean was defined as a body mass index of <23 kg/m2. Participants were categorized into four groups: NAFLD-free lean (reference), NAFLD-free overweight, lean NAFLD, and overweight NAFLD. Compared with the reference, the multivariable-adjusted prevalence ratios (PRs) (95% confidence intervals (CIs)) for VMSs in NAFLD-free overweight, lean NAFLD, and overweight NAFLD were 1.22 (1.06–1.41), 1.38 (1.06–1.79), and 1.49 (1.28–1.73), respectively. For moderate-to-severe VMSs, the multivariable-adjusted PRs (95% CIs) comparing NAFLD-free overweight, lean NAFLD, and overweight NAFLD to the reference were 1.38 (1.10–1.74), 1.73 (1.16–2.57), and 1.74 (1.37–2.21), respectively. NAFLD, even lean NAFLD, was significantly associated with an increased risk of prevalent early-onset VMSs and their severe forms among premenopausal women. Further studies are needed to determine the longitudinal association between NAFLD and VMS risk.

show abstract

Alcohol Consumption Patterns and Risk of Early-Onset Vasomotor Symptoms in Premenopausal Women

Cited by 4 publications

References 45 publications

Frequency of Phytoestrogen Consumption and Symptoms at Midlife among Bangladeshis in Bangladesh and London

Frequency of Phytoestrogen Consumption and Symptoms at Midlife among Bangladeshis in Bangladesh and London

Clinical guidelines for managing menopausal symptoms in women with (a history of) breast cancer

Nonalcoholic Fatty Liver Disease and Risk of Early-Onset Vasomotor Symptoms in Lean and Overweight Premenopausal Women

Contact Info

Product

Resources

About