Alcohol Use and Ethnicity Independently Predict Antiretroviral Therapy Nonadherence Among Patients Living with HIV/HCV Coinfection

Sims, Omar T.; Chiu, Chia-Ying; Chandler, Rasheeta; Melton, Pamela A.; Wang, Kaiying; Richey, Caroline; Odlum, Michelle

doi:10.1007/s40615-019-00630-8

Cited by 3 publications

(3 citation statements)

References 65 publications

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“…In this study we enrolled a large and diverse national sample of adolescents with ZIP Code level data/ census tract/ to examine neighborhood-level characteristics i.e., age, race, ethnicity, and income). Similar to the literature we found that addressing ethnicity and income can play a significant role in improving the efficacy of interventions in RCTs ( Kraemer et al, 2008 , Sims et al, 2020 , Johnson Lyons et al, 2022 ). Importantly, neighborhoods may operate in ways that enable the behaviors of individuals or restrict access to preventive care or health resources ( Diez Roux and Mair, 2010 , Akinyemiju et al, 2013 ), further exacerbating adverse health outcomes.…”

Section: Discussionsupporting

confidence: 87%

Neighborhood-level characteristics as effect modifiers on the efficacy of the MyPEEPS mobile intervention in same-sex attracted adolescent men

Cordoba,

Garofalo,

Kuhns

et al. 2024

Preventive Medicine Reports

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Section: Discussionsupporting

confidence: 87%

Neighborhood-level characteristics as effect modifiers on the efficacy of the MyPEEPS mobile intervention in same-sex attracted adolescent men

Cordoba,

Garofalo,

Kuhns

et al. 2024

Preventive Medicine Reports

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“…Importantly, a recent paper stressed the fact that both adherence to HAART treatment and alcohol consumption should be carefully monitored in this group of patients. Furthermore, higher alcohol consumption per day was positively associated with HAART non-adherence[ 346 ]. Interestingly, high coffee intake is probably associated with reduced liver fibrosis even in HCV/HIV coinfected patients with high alcohol abuse[ 347 ].…”

Section: Hcv/hiv Coinfectionmentioning

confidence: 99%

Hepatitis C virus: A critical approach to who really needs treatment

Voumvouraki¹

2022

WJH

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Introduction of effective drugs in the treatment of hepatitis C virus (HCV) infection has prompted the World Health Organization to declare a global eradication target by 2030. Propositions have been made to screen the general population and treat all HCV carriers irrespective of the disease status. A year ago the new severe acute respiratory syndrome coronavirus 2 virus appeared causing a worldwide pandemic of coronavirus disease 2019 disease. Huge financial resources were redirected, and the pandemic became the first priority in every country. In this review, we examined the feasibility of the World Health Organization elimination program and the actual natural course of HCV infection. We also identified and analyzed certain comorbidity factors that may aggravate the progress of HCV and some marginalized subpopulations with characteristics favoring HCV dissemination. Alcohol consumption, HIV coinfection and the presence of components of metabolic syndrome including obesity, hyperuricemia and overt diabetes were comorbidities mostly responsible for increased liver-related morbidity and mortality of HCV. We also examined the significance of special subpopulations like people who inject drugs and males having sex with males. Finally, we proposed a different micro-elimination screening and treatment program that can be implemented in all countries irrespective of income. We suggest that screening and treatment of HCV carriers should be limited only in these particular groups.

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“…Undoubtedly, attention to both alcohol and substance use are warranted. Alcohol use accelerates HIV and HCV viral replication and worsens liver damage (Lim et al, 2014 ; Szabo et al, 2010 ), and both alcohol and substance use reduces medication adherence and increases the risk of transmission to those living without infection (Massa & Rosen, 2012 ; Sims et al, 2019 ) Despite tobacco use also expediting HCV and HIV disease progression and other negative health outcomes, tobacco use in patients living with HIV/HCV co-infection is rarely addressed in HIV clinical settings and in research. Health professionals and researchers are encouraged to consider intervention approaches that target concurrent alcohol and substance use as a method of reducing the likelihood of tobacco use or intervention approaches that collectively target alcohol, substance, and tobacco use.…”

Section: Discussionmentioning

confidence: 99%

A Cross-Sectional Analysis of Tobacco Use and Concurrent Alcohol and Substance Use Among Patients Living with HIV/HCV Co-infection: Findings from a Large Urban Tertiary Center

Sims

Jackson

Guo

et al. 2020

J Clin Psychol Med Settings

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This study aimed to assess the prevalence of and factors associated with tobacco use among patients living with HIV/HCV co-infection. Patient reported outcomes (PROs) were analyzed of patients living with HIV/HCV co-infection (n = 313) who presented for clinical evaluation and treatment of HCV between 2013 and 2017 at a university-affiliated HIV/HCV Co-infection Clinic. The prevalence of tobacco use in patients living with HIV/HCV co-infection was 48%. Compared to non-smokers, a higher proportion of tobacco smokers had substance use disorders and concurrent alcohol and substance use. In the multivariate analysis, concurrent alcohol and substance use was positively associated with tobacco use. The findings suggest clinical interventions are urgently needed to reduce tobacco use among patients living with HIV/HCV co-infection-a doubly-vulnerable immunocompromised population. Otherwise, failed efforts to dedicate resources and targeted behavioral interventions for this respective population will inhibit survival-especially considering the recent and evolving COVID-19 pandemic.

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Alcohol Use and Ethnicity Independently Predict Antiretroviral Therapy Nonadherence Among Patients Living with HIV/HCV Coinfection

Cited by 3 publications

References 65 publications

Neighborhood-level characteristics as effect modifiers on the efficacy of the MyPEEPS mobile intervention in same-sex attracted adolescent men

Neighborhood-level characteristics as effect modifiers on the efficacy of the MyPEEPS mobile intervention in same-sex attracted adolescent men

Hepatitis C virus: A critical approach to who really needs treatment

A Cross-Sectional Analysis of Tobacco Use and Concurrent Alcohol and Substance Use Among Patients Living with HIV/HCV Co-infection: Findings from a Large Urban Tertiary Center

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