Alcohol Use and Prostate Cancer Risk in US Blacks and Whites

Hayes, Richard B.; Brown, Linda Morris; Schoenberg, Janet B.; Greenberg, Raymond S.; Silverman, Debra T.; Schwartz, Ann G.; Swanson, G. Marie; Bénichou, Jacques; Liff, Jonathan M.; Hoover, Robert N.; Pottern, Linda M.

doi:10.1093/oxfordjournals.aje.a008802

Cited by 71 publications

(66 citation statements)

References 33 publications

(53 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This finding agreed with most studies that reported no association [29]. The one study that investigated the relation separately by race reported a positive association between consumption of large quantities of alcohol and prostate cancer risk that was similar for African-American and white men, and was independent of smoking [30].…”

Section: Discussionsupporting

confidence: 90%

Lifestyle and Prostate Cancer Among Older African-American and Caucasian Men in South Carolina

Sanderson¹,

Coker

Logan³

et al. 2004

Cancer Causes Control

View full text Add to dashboard Cite

Objective-We investigated the association between lifestyle and prostate cancer risk among Caucasian and African-American men, separately.Methods-This population-based case-control study of prostate cancer among men aged 65-79 years was conducted between 2000 and 2002 in South Carolina. Telephone interviews were completed with 416 incident prostate cancer cases ascertained through the South Carolina Central Cancer Registry, and 429 controls identified through the Health Care Financing Administration Medicare beneficiary file (with respective response rates of 71% and 64%).Results-Caucasian men working in production, transportation, and material moving had increased prostate cancer risk (odds ratio [OR]=2.04, 95% confidence interval [CI] 1.17-3.54), while African-American men in the military had reduced prostate cancer risk (OR=0.19, 95% CI 0.05-0.76). Having five or more prostate specific antigen (PSA) tests within the past five years was associated with prostate cancer among Caucasian men; however, African-American men with prostate cancer tended to have fewer PSA tests. Increasing lycopene consumption was associated with a reduced risk of prostate cancer among Caucasian men (p=0.03), but not among AfricanAmerican men.Conclusions-In this population-based case-control study conducted in South Carolina we did not find marked differences in lifestyle factors associated with prostate cancer by race.

show abstract

Section: Discussionsupporting

confidence: 90%

Lifestyle and Prostate Cancer Among Older African-American and Caucasian Men in South Carolina

Sanderson¹,

Coker

Logan³

et al. 2004

Cancer Causes Control

View full text Add to dashboard Cite

show abstract

“…In Britain, tinned baked beans (see below) may be a major effective source of lycopene because of the high bioavailability of lycopene from the tomato sauce. Hayes et al (1996) recently reported a significant trend of increasing risk with increasing alcohol consumption in a large case-control study. However, there was no evidence for such a trend in) our study or in most previous studies (Key, 1995).…”

Section: Discussionmentioning

confidence: 98%

A case-control study of diet and prostate cancer

Key¹,

Silcocks²,

Davey³

et al. 1997

Br J Cancer

299

148

View full text Add to dashboard Cite

Summary We interviewed 328 men diagnosed with prostate cancer before the age of 75 years and 328 age-matched population controls. The principal hypotheses were that risk would increase with a high intake of total or saturated fat and would decrease with a high intake of carotene (P-carotene equivalents) or lycopene. We also examined the associations of other nutrients and foods with risk. There was no evidence for an association between fat intake and risk, although the average fat intake was high and the range of fat intakes was narrow (medians of lower and upper thirds of percentage of energy from fat among controls were 34.3% and 42.9% respectively). Risk was lower in subjects with higher carotene intake: odds ratios 0.65 (95% Cl 0.45-0.94) and 0.76 (0.53-1.10) in the middle and upper thirds of carotene intake respectively (Pfor trend = 0.150). Lycopene was not associated with risk. Among 13 other nutrients examined, the odds ratios in the top third of intake were below 0.

show abstract

“…This result is Epidemiology consistent with several previous reports. With regard to the association between alcohol and prostate cancer by stage, alcohol consumption increased the risk of advanced or fatal prostate cancer, [17][18][19][20] although a recent prospective US cohort study reported a nonsignificant association between alcohol and advanced cancers and an increased risk of nonadvanced cases. 21 Other studies that showed no association between alcohol and prostate cancer might have been affected by detection bias of screening, which would mask an association if heavy drinkers were less likely to get PSA screening.…”

Section: Discussionmentioning

confidence: 99%

Alcohol and smoking and subsequent risk of prostate cancer in Japanese men: The Japan Public Health Center‐based prospective study

Sawada¹,

Inoue

Iwasaki³

et al. 2013

Intl Journal of Cancer

View full text Add to dashboard Cite

Although alcohol and smoking have not been established as risk factors for prostate cancer, they are important risk factors for other human cancers and potentially major avoidable factors. Alcohol drinkers and smokers might be less likely to get screening, which might lead to attenuation of the positive association. Here, we investigated the association of alcohol drinking and smoking and prostate cancer according to stage, as well as prostate cancer detected by subjective symptoms, in a large prospective study among Japanese men. The Japan Public Health Center-based prospective study (JPHC study) was established in 1990 for Cohort I and in 1993 for Cohort II. Subjects were 48,218 men aged 40-69 years who completed a questionnaire, which included their alcohol and smoking habits at baseline, and who were followed until the end of 2010. During 16 years of follow-up, 913 men were newly diagnosed with prostate cancer; of whom 248 had advanced cases, 635 were organlocalized and 30 were of an undetermined stage. Alcohol consumption was dose-dependently associated with advanced prostate cancer [nondrinkers: reference, 0-150 g=week: hazard ratio (HR) 5 1.23, 95% confidence interval (CI) 5 0.83-1.82; 150-300 g=week: HR 5 1.51, 95% CI 5 1.04-2.19; 300 g=week: HR 5 1.41, 95% CI 5 0.97-2.05, p for trend 5 0.02]. The positive association was not substantially changed among cancers detected by subjective symptoms. Smoking was inversely associated with prostate cancer among total subjects, but tended to increase the risk of advanced prostate cancer detected by subjective symptoms. In conclusion, abstinence from alcohol and prohibition of smoking might be important factors in the prevention of advanced prostate cancer.Alcohol and smoking are important risk factors for human cancers and potentially major avoidable factors. The report by the World Cancer Research Fund=American Institute for Cancer Research (WCRF=AICR) on nutrition, physical activity and cancer concluded that the data were too limited to determine an association between alcohol and prostate cancer. 1 Further, a recent meta-analysis of 50 case-control and 22 cohort studies concluded that there was no evidence of a material association between alcohol drinking and prostate cancer. 2 However, questions remain about the effects of alcohol use at higher intake. Given that the proportion of heavy drinkers has been increasing for decades in Japan, 3 research in Japan might help answer these unsolved questions. Moreover, the effects of alcohol in different histological grades of prostate cancer are also controversial. It is possible that previous studies were affected by detection bias associated with screening, such as prostate-specific antigen (PSA) screening, which would mask an association if alcohol drinkers were less likely to get screening.With regard to tobacco, the International Agency for Research on Cancer does not consider prostate cancer to be tobacco-related. 4 A recent meta-analysis of 24 prospective cohort studies showed no increased risk of incident pros...

show abstract

Alcohol Use and Prostate Cancer Risk in US Blacks and Whites

Cited by 71 publications

References 33 publications

Lifestyle and Prostate Cancer Among Older African-American and Caucasian Men in South Carolina

Lifestyle and Prostate Cancer Among Older African-American and Caucasian Men in South Carolina

A case-control study of diet and prostate cancer

Alcohol and smoking and subsequent risk of prostate cancer in Japanese men: The Japan Public Health Center‐based prospective study

Contact Info

Product

Resources

About