Alcohol Use Disorder and Depressive Disorders

McHugh, R. Kathryn

doi:10.35946/arcr.v40.1.01

Cited by 299 publications

(275 citation statements)

References 54 publications

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“…Consistent with epidemiological findings that substance use disorders are commonly comorbid with PTSD [ 118 , 119 , 120 , 121 ] and MDD [ 122 , 123 ], there was a higher prevalence of history of alcohol abuse/dependence in MCI group compared to the other two groups (44% vs. 19% and 23% in intermediate and CN). Although post-hoc analysis suggested that history of alcohol use disorder was not significantly associated with MCI status in the present study, like PTSD and MDD, heavy alcohol use has been associated with deleterious effects on the hippocampus [ 124 ] and cognitive function [ 125 , 126 , 127 , 128 ].…”

Section: Discussionsupporting

confidence: 83%

The Prevalence of Mild Cognitive Impairment in a Convenience Sample of 202 Gulf War Veterans

Chao

2020

IJERPH

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Gulf War Illness (GWI) is a chronic, multisymptom disorder estimated to affect approximately 25–32% of Gulf War veterans (GWVs). Cognitive dysfunction is a common symptom of GWI. On the continuum of cognitive decline, mild cognitive impairment (MCI) is conceptualized as a transitional phase between normal aging and dementia. Individuals with MCI exhibit cognitive decline but have relatively spared activities of daily function and do not meet criteria for dementia. The current study sought to investigate the prevalence of MCI in a convenience sample of 202 GWVs (median age: 52 years; 18% female). Twelve percent of the sample (median age: 48 years) had MCI according to an actuarial neuropsychological criterion, a rate materially higher than expected for this age group. GWVs with MCI also had a smaller hippocampal volume and a thinner parietal cortex, higher rates of current posttraumatic stress disorder and major depressive disorder compared to GWVs without MCI. Because people with MCI are more likely to progress to dementia compared to those with normal cognition, these results may portend future higher rates of dementia among deployed GWVs.

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Section: Discussionsupporting

confidence: 83%

The Prevalence of Mild Cognitive Impairment in a Convenience Sample of 202 Gulf War Veterans

Chao

2020

IJERPH

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“…Alcohol use disorder: Alcohol use disorder (AUD) was identi ed based on the 10-item Alcohol Use Disorder Identi cation Test (AUDIT), a screening instrument developed by the World Health Organization (WHO), which includes questions on the patterns of hazardous and harmful alcohol use and dependence symptoms in the past 12 months [24]. The respondents were classi ed into three levels based on the AUDIT scores: non-problem drinkers (0-7), hazardous drinkers (8)(9)(10)(11)(12)(13)(14)(15), and harmful-dependent drinkers [24].…”

Section: Methodsmentioning

confidence: 99%

Socio-economic inequalities in the association between alcohol-use disorder and depressive disorder among Thai adults: a population-based study

Assanangkornchai

Nontarak

Aekplakorn

et al. 2020

Preprint

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Background: Previous evidence indicates significant associations between depressive disorders and alcohol use disorder (AUD) and their strong links with social conditions. This study aims to investigate the association between major depressive episode (MDE) and AUD across various socio-economic groups.Methods: We analysed data from the 2014 Thai National Health Examination Survey containing a random sample of 13,177 adults aged >20 years from the general population. The Alcohol Use Disorder Identification Test was used to classify respondents into non-problem drinking (score 0-7), hazardous drinking (score 8-15), and harmful-dependent drinking (score 16-40). MDE was identified using questions based on the DSM-IV. Adjusted odds ratios (AOR) and 95% confidence intervals (CI) were calculated using multinomial logistic regression to determine the strength of associations between MDE as a predictor and AUD as an outcome variable across different socio-economic levels.Results: The prevalence of MDE, hazardous, and harmful-dependent drinking was 2.5%, 10.3%, and 1.9%, respectively. The association between MDE and AUD was modified by wealth index, education level and area of residence. AORs for the association between MDE and harmful-dependent drinking were high among those in the highest (AOR=8.68, 95% CI: 5.34, 14.11) and lowest (AOR=7.14, 95% CI: 3.71, 13.73) levels of wealth index but not significant among those in the middle level (AOR=1.78, 95% CI: 0.74, 4.25). Education had the strongest effect on the relationship between MDE and harmful-dependent drinking (AOR=16.0, 95% CI: 10.30, 24.90 among those completing secondary school or higher and AOR=1.44, 95% CI: 0.63, 3.33 among those completing primary school only). The association between MDE and harmful-dependent drinking was higher among people who lived in urban areas (AOR=8.50, 95% CI: 5.50, 13.13) compared to those living in rural areas (AOR=4.73, 95% CI: 3.31, 6.77).Conclusion: Socio-economic factors modify the association between alcohol use disorder and major depressive disorder among Thai people.

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“…Treating depression may decrease pain conditions [36], especially if both pain and depression are most severe at the beginning of treatment [35]. Similarly, the synergistic effects of comorbid depression and ALC have been associated with greater severity for both disorders [37].…”

Section: Discussionmentioning

confidence: 99%

Chronic Pain in Relation to Depressive Disorders and Alcohol Abuse

Maleki

Oscar‐Berman

2020

Brain Sciences

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Chronic pain disorders have been associated separately with neuropsychiatric conditions such as depression and alcohol abuse. However, in individuals who suffer from non-cancer chronic pain disorders, it is not clear if the burden of depressive disorders is similar for those with and without a history of alcohol abuse. Using data from the Collaborative Psychiatric Epidemiology Surveys (CPES), we found depressive disorders to have a high burden in men and women with a history of alcohol abuse, independently of the presence or absence of chronic pain. We also found that, although the incidence of persistent depressive disorder was comparable in men and women with a history of alcohol abuse, and significantly higher than in control men and women, the incidence of a major depressive episode was higher in women with a history of alcohol abuse independently of the presence or absence of chronic pain. The age of onset of depressive disorders, independently of pain status, was younger for individuals with a history of alcohol abuse. The findings of this study have important implications for the clinical management of individuals who suffer from chronic pain comorbidly with depression and/or alcohol abuse.

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Alcohol Use Disorder and Depressive Disorders

Cited by 299 publications

References 54 publications

The Prevalence of Mild Cognitive Impairment in a Convenience Sample of 202 Gulf War Veterans

The Prevalence of Mild Cognitive Impairment in a Convenience Sample of 202 Gulf War Veterans

Socio-economic inequalities in the association between alcohol-use disorder and depressive disorder among Thai adults: a population-based study

Chronic Pain in Relation to Depressive Disorders and Alcohol Abuse

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