Alcoholic Liver Disease Complicated by Deep Bleeding into the Muscles or Retroperitoneum: Report of Three Cases and a Review of the Literature

Abstract

We herein report three cases of alcoholic cirrhosis complicated by deep bleeding. In two of the three cases, intramuscular or retroperitoneal hematomas developed spontaneously. In contrast, in the remaining case, an intramuscular hematoma developed after trauma. In the former two patients, the intramuscular hematomas recurred at other sites during hospitalization. All three patients received conservative therapy, and one patient with a retroperitoneal hematoma underwent transcatheter arterial embolization. All of the patients eventually died of liver failure. The occurrence of severe alcoholic liver disease with deep bleeding has recently been reported with increasing frequency, and clinicians should bear this condition in mind as a life-threatening complication of alcoholic liver disease.

‘Expanding before my very eyes!’: spontaneous axillary artery branch bleeding resulting in a large, subpectoral haematoma

“…Spontaneous arterial bleeding is unusual and as such requires a high index of suspicion and rapid intervention due to the significant blood loss which results. 1 2 There are documented cases of spontaneous arterial bleeding in patients with Ehlers-Danlos syndrome, Marfan syndrome, with liver disease 3 or chronic renal failure, 4 on immunosuppressive medication, 5 etc, but spontaneous arterial bleeding especially in the absence of an aneurysm is generally rare. Endovascular approaches such as embolisation or stent grafting provide an alternative and/or additional treatment option to open vascular repair and will often be preferred if available, especially in a haemodynamically stable patient with atraumatic bleeding such as was the case in this patient.…”

Spontaneous iliopsoas muscle hematoma mimicking avascular necrosis in alcoholic liver cirrhosis: a case report

“…Iliopsoas muscle hematoma mostly occurs in patients with clotting difficulties either spontaneously or secondary to trauma, and it is a rare lesion in patients with liver cirrhosis (LC) (1)(2)(3). Clinical signs and symptoms of iliopsoas muscle hematoma include groin pain or swelling and pelvic, back, or lower abdominal pain.…”

Ecchymoma to Liver Cirrhosis: Report of a Case and a Review otfh e Literature

“…However, both patients were died of complications in hospitalization. Masaaki Takamura [4] reported three cases of alcoholic cirrhosis complicated by deep bleeding into the muscles or retroperitoneum. All of patients were died one month after the onset of this rarely ecchymoma complication that causing liver failure.…”