Aldosteronstoffwechsel bei Nierenarterienstenose

Kaufmann, W.; Steiner, Beat; Dürr, F.; Nieth, H; Behn, Claus

doi:10.1007/bf01746127

Cited by 14 publications

(1 citation statement)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The finding of a lower SBF in EH and in patients with RAS could be especially important in the metabolism of aldosterone and other steroids, which are inactivated to a high degree by the liver.3" Previous investigations by our group32 showed that the mean metabolic clearance rate of aldosterone, measured by a constant infusion technique, was 46% lower (P < 0.001) in patients with EH than in healthy subjects. In addition, Kaufmann et al 33 also reported a marked decrease in the metabolic clearance rate of aldosterone in patients with RAS, which partially normalized after corrective surgery. However, the decrease in SBF was only 10% in EH and could thereby account for only a part of the observed 46% decrease in metabolic clearance in EH.…”

Section: Methodsmentioning

confidence: 96%

Splanchnic blood flow in essential hypertension and in hypertensive patients with renal artery stenosis.

Messerli¹,

Genest²,

Nowaczynski³

et al. 1975

Circulation

View full text Add to dashboard Cite

SUMMARYSplanchnic blood flow (SBF) was measured simultaneously with cardiac output (dye dilution) and intraarterial blood pressure by constant infusion of indocyanine green in 11 control subjects, 13 patients with essential hypertension (EH) and seven hypertensive patients with renal artery stenosis (RAS). The cardiac index (CI) was lower (P < 0.05) in patients with EH (3.17 ± 0.07 L/min/m2) (mean i SEMI) than in control subjects (3.43 ± 0.09). Associated with the lower CI was a significantly (P < 0.01) lower SBF same group reported a mean SBF of 755 ml/min/m2 in 41 hypertensive subjects and 798 ml/min/m2 in their 21 normal controls.2 In contrast, Pippig and Schmitt,3 using colloidal chromic-32 phosphate and an external counting system, reported a 20% lower value in 45 essential hypertensive subjects than in 40 normal controls. Other than these contradictory reports, no conclusive data on this subject have been presented. In addition, no data were provided about the type and stage of hypertension studied and obstructive lesions of the renal arteries were not eliminated in patients with EH.The above fact is of considerable importance because a reduction in SBF could be expected to slow down the metabolism of physiological and pharmacological substances by the liver. This in turn might cause an increased plasma level of these agents. We have measured SBF in well-defined hypertensive patients and control subjects according to the principle of Bradley et al.4 by a constant infusion of indocyanine green (ICG).5 Cardiac output and intra-

show abstract

Section: Methodsmentioning

confidence: 96%

Splanchnic blood flow in essential hypertension and in hypertensive patients with renal artery stenosis.

Messerli¹,

Genest²,

Nowaczynski³

et al. 1975

Circulation

View full text Add to dashboard Cite

show abstract

Carbonic Esters

Buysch

2000

Ullmann's Encyclopedia of Industrial Chemistry

View full text Add to dashboard Cite

The article contains sections titled: 1. Introduction 2. Properties 3. Production 3.1. Phosgenation of Alcohols 3.2. Phosgenation of Phenols 3.3. Oxidative Carbonylation of Alcohols 3.4. Oxidative Carbonylation of Phenols 3.5. Oxidative Carbonylation of Alcohols with NO x 3.6. Carbonic Esters from Oxalic Esters 3.7. Electrochemical Oxidative Carbonylation of Alcohols 3.8. Reaction of CO 2 with Oxiranes 3.9. Reactions of Alcohols with Urea 3.10. Reaction of Phenols with Urea 3.11. Miscellaneous Reactions of CO 2 to Form Carbonates 3.12. Transesterification 3.13. Cyclic Carbonic Esters 4. Environmental Protection and Toxicology 5. Quality Specifications 6. Analysis 7. Storage and Transportation 8. Uses 8.1. Direct Uses 8.2. Use for Chemical Synthesis 9. Economic Aspects

show abstract

Renin-Angiotensin-Aldosteronsystem bei Störungen der Blutdruckregulation

Kaufmann

1968

Verhandlungen Der Deutschen Gesellschaft Für Innere Medizin

View full text Add to dashboard Cite

Aldosteronstoffwechsel bei Nierenarterienstenose

Cited by 14 publications

References 29 publications

Splanchnic blood flow in essential hypertension and in hypertensive patients with renal artery stenosis.

Splanchnic blood flow in essential hypertension and in hypertensive patients with renal artery stenosis.

Carbonic Esters

Renin-Angiotensin-Aldosteronsystem bei Störungen der Blutdruckregulation

Contact Info

Product

Resources

About