Alemtuzumab, total skin electron beam, and non‐myeloablative allogeneic haematopoietic stem‐cell transplantation in advanced sezary syndrome: a retrospective cohort study

Abstract

To the Editor Atopic dermatitis (AD) or eczema is a chronic inflammatory skin disease associated with arthritis of inflammatory aetiology such as rheumatoid arthritis. 1 To date, the association between AD and non-inflammatory arthritis remains unknown. This study sought to determine whether AD is associated with increased risk of osteoarthritis (OA) in adults from the 1999-2006 National Health and Nutrition Examination Survey (NHANES), a national representative database of health and

How Far Can We Go? Tailoring Treatment in Advanced Stage Mycosis Fungoides/Sezary Syndrome

“…[4] Sequencing therapies to achieve the best response preallogeneic stem cell transplantation is as important as considering the potential modifications on immune system modulation that might impact the transplant outcomes. [5][6][7][8] Assessing tumor burden by direct skin examination, PET-CT, and flow cytometry are the classic established methods to evaluate the disease response to therapies. [9] Still, new drugs such as anti-CCR4 and CD30 monoclonal antibodies require in-depth immunotypic analysis of normal and neoplastic populations to understand our patients' evolution better.…”