2002
DOI: 10.7326/0003-4819-136-10-200205210-00009
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Alendronate Improves Bone Mineral Density in Elderly Women with Osteoporosis Residing in Long-Term Care Facilities

Abstract: Alendronate increased BMD at both the spine and hip in elderly female residents of long-term care facilities.

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Cited by 113 publications
(111 citation statements)
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“…This analysis suggests that, after the fourth study, the accumulative data are adequate to conclude that bisphosphonates did significantly reduce hip fracture risk. The acronyms of and publication dates of the trials are as follows: 1, Storm et al 1990 (23) ; 2, Harris et al 1993 (24) ; 3, Liberman et al 1995 (7) ; 4, Black et al 1996 (6) ; 5, Cummings et al 1998 (19) ; 6, Bonnick et al 1998 (26) ; 7, Pols et al 1999 (20) ; 8, Greenspan et al 2002 (25) ; 9, Harris et al 1999 (21) ; 10, Reginster et al 2000 (9) ; 11, McClung et al 2001 (8) ; 12, McCloskey et al 2004. (22) sis.…”
Section: Figmentioning
confidence: 99%
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“…This analysis suggests that, after the fourth study, the accumulative data are adequate to conclude that bisphosphonates did significantly reduce hip fracture risk. The acronyms of and publication dates of the trials are as follows: 1, Storm et al 1990 (23) ; 2, Harris et al 1993 (24) ; 3, Liberman et al 1995 (7) ; 4, Black et al 1996 (6) ; 5, Cummings et al 1998 (19) ; 6, Bonnick et al 1998 (26) ; 7, Pols et al 1999 (20) ; 8, Greenspan et al 2002 (25) ; 9, Harris et al 1999 (21) ; 10, Reginster et al 2000 (9) ; 11, McClung et al 2001 (8) ; 12, McCloskey et al 2004. (22) sis.…”
Section: Figmentioning
confidence: 99%
“…Between 1990 and 2004, there were 12 eligible RCTs involving 18,667 individuals (range per study, 66-5445), (6)(7)(8)(9)(19)(20)(21)(22)(23)(24)(25)(26) among whom 263 hip fractures were observed. Three RCTs related to etidronate treatment (27)(28)(29) were excluded from the analysis because no hip fractures were ascertained during the trial period.…”
Section: Characteristics Of Studiesmentioning
confidence: 99%
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“…Greenspan et al demonstrated the utility of alendronate in improving BMD in nursing home residents. 61 A more recent study by the same author tested the safety and efficacy of single-dose zoledronic acid for osteoporosis in a population of nursing home residents. 62 There was no difference in terms of the incidence of fractures between the treatment and placebo groups.…”
Section: Pharmacologicalmentioning
confidence: 99%