This collaborative volume examines revolts and resistance to the successor states formed after Alexander the Great’s conquest of the Persian Empire, as a transregional phenomenon. The editors have assembled an array of specialists in the study of the various regions and cultures of the Hellenistic world ‒ Judea, Egypt, Babylonia, Central Asia, and Asia Minor ‒ in an effort to trace comparisons and connections between episodes and modes of resistance. The volume seeks to unite the currently dominant social-scientific orientation to ancient resistance and revolt with perspectives, often coming from religious studies, that are more attentive to local cultural, religious, and moral frameworks. In re-assessing these frameworks, contributors move beyond Greek/non-Greek binaries to examine resistance as complex and entangled: acts and articulations of resistance are not purely nativistic or ‘nationalist’, but conditioned by local traditions of government and historical memories of prior periods, as well as emergent trans-regional Hellenistic political and cultural idioms. The book is organized into three parts. The first part investigates the Great Theban Revolt and the Maccabean Revolt, the central cases for large, organized, and prolonged military uprisings against the Hellenistic kingdoms. The second part examines the full gamut of indigenous self-assertion and resistant action, including theologies of monarchic inadequacy, patterns of historical periodization and textual interpretation, and claims to sites of authority. The volume’s final part turns to the more ambiguous assertions of local autonomy and identity that emerge in the frontier regions that slipped in and out of the grasp of the great Hellenistic powers.