Alexandrite Laser for the Treatment of Resistant and Hypertrophic Port Wine Stains: A Clinical, Histological and Histochemical Study

Grillo, Emiliano; González-Muñoz, P.; Boixeda, P.; Cuevas, A.; Vañó, S.; Jaén, P.

doi:10.1016/j.adengl.2016.04.005

Cited by 1 publication

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The current treatment options for PDL‐resistant PWS include the 532‐nm potassium titanyl phosphate (KTP) laser, 755‐nm alexandrite laser, 1064‐nm neodymium:yttrium–aluminum–garnet (Nd:YAG) laser and intense pulsed light (IPL) . However, these methods for treating PDL‐resistant PWS lesions rarely show a satisfactory level of efficacy and may cause persistent adverse effects or cosmetic disfigurement …”

Section: Introductionmentioning

confidence: 99%

Retrospective study of photodynamic therapy for pulsed dye laser‐resistant port‐wine stains

Han

Ying

Zhang

et al. 2020

The Journal of Dermatology

View full text Add to dashboard Cite

Pulsed dye laser‐resistant port‐wine stains present a therapeutic challenge. The aim of this study was to evaluate the efficacy and safety of photodynamic therapy for treating these lesions. A total of 67 patients with pulsed dye laser‐resistant cervicofacial port‐wine stains were retrospectively assessed after undergoing photodynamic therapy mediated with a combination of hemoporfin and 532‐nm light. For objective evaluation of photodynamic therapy efficacy, first, the colorimetric changes in the port‐wine stain lesions were evaluated according to the L*a*b* color coordinate system, then the values of color changes (ΔE) and blanching rate were calculated. For subjective evaluation of improvement, photographs taken before and after photodynamic therapy were evaluated by three independent assessors blindly. Patient satisfaction was also used as a factor in the subjective evaluation. Adverse events were recorded after treatment. The median ΔE decreased significantly from the pretreatment value of 13.42 to 9.90 at the 2‐month follow up (P < 0.001). The median blanching rate of port‐wine stains was 28.04% after an average of 1.21 sessions of photodynamic therapy. Based on the overall visual assessment, 46.2% patients showed excellent or good levels of improvement (>50% color blanching). Adverse events were minimal, transient and self‐limiting. In conclusion, photodynamic therapy serves as an alternative means to treat pulsed dye laser‐resistant port‐wine stains.

show abstract

Section: Introductionmentioning

confidence: 99%