Alexithymia in multiple sclerosis: relationship with fatigue and depression

Bodini, Benedetta; Mandarelli, Gabriele; Tomassini, Valentina; Tarsitani, Lorenzo; Pestalozza, I.; Gasperini, Claudio; Lenzi, Gian Luigi; Pancheri, P.; Pozzilli, Carlo

doi:10.1111/j.1600-0404.2007.00969.x

Cited by 54 publications

(52 citation statements)

References 39 publications

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“…The prevalence of fatigue in the wider MS patient population is high, with prevalence ranging from 53% to 80% (Alarcia et al, 2005;Bodini et al, 2007;Hatzakis et al, 2005;Lobentanz et al, 2004;Soyuer, Mirza, & Oztürk, 2005). Fatigue was found in 73.1% of our patients.…”

Section: Discussionmentioning

confidence: 96%

“…One plausible explanation for the adverse impact of fatigue on HRQoL may be that it impacts upon the physical activities that patients can perform. Depression is also a common symptom in MS, with various studies reporting prevalence ranging from 27% to 72% (Ayatollahi et al, 2007;Bodini et al, 2007;Drulovic et al, 2007;Johnson, 2008;S'a, 2008). In this study, the prevalence of depression was 66%.…”

Section: Discussionmentioning

confidence: 98%

“…As the most common psychiatric disorder accompanying MS (Bodini et al, 2007;Figved et al, 2005;Hart, Fonareva, Merluzzi, & Mohr, 2005;Lobentanz et al, 2004), depression is often by far the strongest predictor for reduced QOL (Fruehwald, LoefflerStastka, Eher, Saletu, & Baumhacki, 2001). Many previous studies (Kaya et al, 2003;Merkelbach, Sittinger, & Koenig, 2002;Newland, 2006) have found that depression is negatively associated with decreased overall HRQoL in MS subjects.…”

mentioning

confidence: 97%

“…Fatigue is often considered a state of exhaustion distinct from depressed mood or physical weakness (Krupp, 2003). The prevalence of fatigue in MS is high, with 53% to 80% of the subjects reporting significant problems of fatigue across different studies (Alarcia, Ara, Martin, Bertol, & Bestue, 2005;Bodini et al, 2007;Johnson, 2008;Hatzakis et al, 2005;Lobentanz et al, 2004;McAllister & Krupp, 2005;Randolph & Arnett, 2005). Fatigue has detrimental effects on activities of daily living (e.g., while doing housework, visiting friends, moving around, and doing shopping), social and occupational obligations, and overall well-being (Krupp, 2003;Lerdal, Gulowsen Celiusb, Kruppc, & Dahl, 2007;Strober & Arnett, 2005).…”

mentioning

confidence: 98%

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Quality of Life in Patients With Multiple Sclerosis in Turkey: Relationship to Depression and Fatigue

Tanrverdi

Okanl²,

Sezgin³

et al. 2010

Journal of Neuroscience Nursing

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The purposes of this study were to assess the self-reported quality of life (QOL) in a group of Turkish patients with multiple sclerosis (MS) and to analyze whether the QOL was associated with fatigue and depression. The study used a descriptive design. A number of evaluation scales were administered to a study sample comprising 47 outpatients. The Short Form 36 for QOL, the Beck Depression Inventory for Depression, and the Visual Analogue Scale for Fatigue were used. The mean score for general QOL was 34.8 and indicated low QOL in MS patients. The results of our study have also shown that fatigue and depression strongly influence QOL in Turkish MS patients. Our findings may have important implications for the overall care of MS patients. The QOL of MS patients was affected negatively. Both fatigue and depression are common and treatable manifestations of MS, and these symptoms should be screened carefully in all MS patients. Care of MS patients requires the collaboration of all team members. Nurses have a key role as part of this team through the continuity of the care they provide and interaction with patients. Awareness of depression and fatigue can contribute to the nurses' ability to provide psychological support and enhance the QOL in MS patients.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 98%

mentioning

confidence: 97%

mentioning

confidence: 98%

See 2 more Smart Citations

Quality of Life in Patients With Multiple Sclerosis in Turkey: Relationship to Depression and Fatigue

Tanrverdi

Okanl²,

Sezgin³

et al. 2010

Journal of Neuroscience Nursing

View full text Add to dashboard Cite

show abstract

“…The difficulties involved in therapeutic approaches towards frequent and disabling conditions that are likely to be misunderstood and undervalued by others may influence such patients' behavior. Indeed, some studies show correlations between levels of depression and fa-tigue 16 , and both of these with alexithymia 17 . Our impression has been that, even for patients who are not chronically depressed and/or anxious, fatigue could alter the way in which they see themselves, thus subsequently affecting how they interact with others.…”

mentioning

confidence: 99%

Correlation between fatigue and self-esteem in patients with multiple sclerosis

Fragoso

Silva

Finkelsztejn

2009

Arq. Neuro-Psiquiatr.

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-Objective: To assess the possible association of fatigue with self-esteem in multiple sclerosis (MS) patients. Method: Thirty patients were prospectively assessed. None of them presented moderate or severe depression or anxiety and their degree of disability was low (EDSS≤3.5). They had been clinically stable for at least three months and had been receiving the same medication for at least six months. Socioeconomic level was assessed. Severity of fatigue and self-esteem were evaluated using specific, validated scales. Patients with moderate to severe anxiety and/or depression were excluded. Results: Low self-esteem correlated with fatigue (p=0.01), but not with any other variables, such as age, gender, EDSS, MS duration, number of relapses, mild depression and/or anxiety. Conclusion: Greater severity of fatigue in MS correlates with low self-esteem, thus suggesting that this chronic complaint that affects so many patients can interfere with the way in which they see and value themselves.KEY WORDS: fatigue, self-esteem, depression, anxiety, multiple sclerosis. Correlação entre gravidade da fadiga e baixa estima na esclerose múltiplaResumo -Objetivo: Avaliar a possível associação entre fadiga e autoestima em pacientes com esclerose múltipla (EM). Método: Trinta pacientes foram avaliados de forma prospectiva. Nenhum deles apresentava depressão ou ansiedade moderada ou grave, e o grau de incapacidade foi baixo (EDSS≤3,5). Eles estavam clinicamente estáveis por pelo menos três meses e estavam recebendo a mesma medicação por pelo menos seis meses. O nível socioeconômico foi avaliado. A gravidade da fadiga e a autoestima foram avaliadas pelo uso de escalas especificas e validadas. Pacientes com ansiedade e/ou depressão moderadas ou graves foram excluídos. Resultados: Baixa autoestima se mostrou correlacionada com fadiga (p=0,01), porém não relacionada a qualquer outra variável, como sexo, idade, EDSS, duração da EM, número se surtos, depressão e/ou ansiedade leves. Conclusão: Maior gravidade de fadiga na EM se correlaciona com baixa autoestima, sugerindo assim que esta queixa crônica que afeta tantos pacientes pode interferir com a maneira pela qual eles se vêem e se valorizam. PALAVRAS-CHAVE: fadiga, autoestima, depressão, ansiedade, esclerose múltipla.

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Longitudinal study of alexithymia and multiple sclerosis

et al. 2013

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ObjectiveThe aim of this study was to investigate the course of alexithymia and its relation with anxiety and depression in patients with multiple sclerosis (MS), over a period of 5 years.MethodsSixty-two MS patients were examined at two timepoints, 5 years apart, and they answered questionnaires collecting socio-demographic, medical, and psychological data (depression, anxiety, alexithymia).ResultsOur data show that emotional disorders remain stable over time in patients with MS, particularly as regards alexithymia and anxiety. Conversely, the rate of depression decreased between the two evaluations, falling from 40% to 26%. The two dimensions of alexithymia (i.e., difficulty describing and difficulty identifying feelings) were correlated with anxiety and depression, whereas the third component of alexithymia (externally oriented thinking) was independent, and was the only component to change over time, with a significant fall observed at 5 years.ConclusionAlexithymia was associated with increased severity of anxiety and attack relapses.

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Alexithymia in multiple sclerosis: relationship with fatigue and depression

Abstract: Alexithymia was associated with increased severity of fatigue and depression.

Cited by 54 publications

References 39 publications

Quality of Life in Patients With Multiple Sclerosis in Turkey: Relationship to Depression and Fatigue

Quality of Life in Patients With Multiple Sclerosis in Turkey: Relationship to Depression and Fatigue

Correlation between fatigue and self-esteem in patients with multiple sclerosis

Longitudinal study of alexithymia and multiple sclerosis

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