Alginate-based composite sponge containing silver nanoparticles synthesized in situ

Antioxidative and antiinflammatory activities of quercetin-loaded silica nanoparticles

“…Considerable evidence suggests that the cytotoxicity of silver nanoparticles results from their interaction with mitochondria and induction of the apoptosis pathway via the production of ROS. A dramatic increase in ROS levels has been found, suggesting that oxidative stress is an important mediator of cytotoxicity [35][36][37][38]. Free quercetin and the quercetin-loaded silica nanoparticles showed cell viabilities comparable to that of the control, as shown in Figure 5.…”

Functional bioreactor characterization to assess potentials of nanocomposites based on different alginate types and silver nanoparticles for use as cartilage tissue implants

“…This result can be probably explained by a more favorable spatial conformation of G units and GG blocks. In specific, it was shown that AgNPs stabilized by electrostatic interactions with a capping agent, such as alginate, have negative ζ potentials . Interactions of cations with carboxyl groups have been shown to decrease the ζ potential and increase the tendency for agglomeration of NPs, which has led to the assumption that carboxyl groups may have a critical role in NP stabilization .…”

The preparation of alginate–AgNPs composite fiber with green approach and its antibacterial activity

“…These formed silver nanoparticles could probably be capped and stabilized by alginate. The possible reason is alginate fragments containing carboxylic groups can provide nanoparticles with a negative charge and stability against agglomeration due to electrostatic repulsion [17][18][19].…”