Alien hand and leg as the presenting feature of probable sporadic Creutzfeldt-Jakob disease: A rare presentation of a rare disease

Kumawat, Banshi Lal; Sharma, C. M.; Nath, Kunal; Acharya, Mihir; Khandelwal, Dinesh; Jain, Deepak

doi:10.4103/0972-2327.144278

Cited by 2 publications

(1 citation statement)

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“…Ghazal Haeri et al reported two cases of alien leg syndrome without upper limb involvement, both due to underlying corticobasal syndrome [ 6 ]. Banshi Lal Kumawat et al reported a case of alien hand and leg as a presenting symptom of sporadic CJD, the patient rapidly deteriorated and developed truncal ataxia and cognitive decline within 15 days of admission [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Alien Hand Syndrome Unveiled in a Patient With Right Middle Cerebral Artery Stroke

Rashwan,

Elagha,

Aldaham

et al. 2024

Cureus

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Alien hand syndrome (AHS) is a rare but significant disorder, characterized by involuntary and often complex movements of one’s hand. These movements seem to occur independently and unconsciously, separate from a person's intended actions. We report a case of a 70-year-old male who presented to the emergency department with left sided hemiplegia following a stroke in the right middle cerebral artery (MCA) that affected the right temporal, parietal and internal capsule region. Upon additional inquiry, the patient reported experiencing involuntary, abrupt movements in his left upper and lower limbs particularly while attempting voluntary movements. As per the patient, these symptoms occurred prior to the onset of limb weakness. The diagnosis of AHS was made after excluding other differentials based on the clinical, metabolic and radiological picture. Our patient exhibited unique symptoms and had a different presentation from that mentioned in the literature, as the onset of symptoms preceded the development of limb weakness typically associated with stroke. Involvement of the upper and lower limb and onset of symptoms prior to limb weakness make this case exceptionally rare. Moreover, acknowledging alien hand/limb syndrome as a distinct condition, separate from the broad category of post-stroke movement disorder, carries significant implications for both the management and prognosis of affected individuals.

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Section: Discussionmentioning

confidence: 99%