SummaryIn the world of emerging wireless networks, interference poses a significant challenge to reliable wireless communication. Additionally, these networks are prone to path loss and blockages, which can be addressed by utilizing the advanced technology of multihop communication with instantaneous relay (IR). However, scenarios involving IR‐assisted networks are considered instances of multihop communications that face potential obstacles caused by interference. As a result, multiple interference management approaches exist to tackle this interference issue, among which aligned interference neutralization (AIN) is a state‐of‐the‐art technology that seamlessly unifies two established interference management strategies: interference alignment (IA) and interference neutralization (IN). Therefore, this paper presents a novel tristaged AIN scheme to mitigate interference in a multicellular multiple‐input multiple‐output (MIMO) interference multiple access channel (IMAC). In the proposed scheme, the initial stage‐1 involves transmitting message signals from individual transmitters or users to the IR and the receiving base stations (BSs). In stage‐2, the IR neutralizes half of the interference signals by performing IN. Finally, in stage‐3, IA is carried out at the receiver BS terminals, aligning the remaining interference signals equally within the available dimensions. Based on this proposed approach, we determined that for an IR‐aided multicellular MIMO IMAC, the achievable degree of freedom (DoF) is 2N. The proposed approach's robustness and effectiveness have been analyzed through extensive simulations, and these simulation results indicated that the proposed approach outperforms other benchmark interference management techniques in terms of DoF and sum rate, thereby improving user performance.