Aliskiren Reduces Morning Blood Pressure in Hypertensive Patients with Diabetic Nephropathy on Hemodialysis

Takenaka, Tsuneo; Okayama, Mika; Kojima, Eriko; Nodaira, Yuka; Arai, Jonde; Uchida, Kazuhiko; Kikuta, Tomohiro; Sueyoshi, Keita; Hoshi, Hitoshi; Watanabe, Yusuke; Takane, Hiroshi; Suzuki, Hiromichi

doi:10.3109/10641963.2013.780066

Cited by 3 publications

(2 citation statements)

References 24 publications

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“…In 2008, a new class of hypertension medications was approved for use in Canada, called direct renin inhibitors. Currently, aliskiren is the only medication within this class approved for use and appears to have weight neutral effects (0.0–1.0 kg 176 , 178 ).…”

Section: Antidepressantsmentioning

confidence: 99%

Medications that cause weight gain and alternatives in Canada: a narrative review

Wharton¹,

Raiber²,

Serodio³

et al. 2018

DMSO

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BackgroundThe cause of the obesity epidemic is multifactorial, but may, in part, be related to medication-induced weight gain. While clinicians may strive to do their best to select pharmacotherapy(ies) that has the least negative impact on weight, the literature regarding the weight effects of medication is often limited and devoid of alternative therapies.ResultsAntipsychotics, antidepressants, antihyperglycemics, antihypertensives and corticosteroids all contain medications that were associated with significant weight gain. However, there are several medication alternatives within the majority of these classes associated with weight neutral or even weight loss effects. Further, while not all of the classes of medication examined in this review have weight-favorable alternatives, there exist many other tools to mitigate weight gain associated with medication use, such as changes in dosing, medication delivery or the use of adjunctive therapies.ConclusionMedication-induced weight gain can be frustrating for both the patient and the clinician. As the use of pharmaceuticals continues to increase, it is pertinent for clinicians to consider the weight effects of medications prior to prescribing or in the course of treatment. In the case where it is not feasible to make changes to medication, adjunctive therapies should be considered.

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Section: Antidepressantsmentioning

confidence: 99%

Medications that cause weight gain and alternatives in Canada: a narrative review

Wharton¹,

Raiber²,

Serodio³

et al. 2018

DMSO

View full text Add to dashboard Cite

show abstract

“…Takenaka et al . reported that the alsikiren reduced morning blood pressure measured at home in HD patients with diabetic nephropathy [26]. These lines of evidence suggested that alsikiren has beneficial effects for blood pressure control in HD patients.…”

Section: Direct Renin Inhibitor In Hd Patinetsmentioning

confidence: 99%