Alkaline Mineral Supplementation Decreases Pain in Rheumatoid Arthritis Patients: A Pilot Study

Abstract

Abstract:The aim of this pilot study was to investigate the efficacy of an alkaline mineral supplement as a means of suppressing disease activity in rheumatoid arthritis (RA) patients, and to check whether any change occurs in the circulating beta-endorphin concentration. Thirty-seven patients with moderately active RA of at least two years duration, who were receiving stable pharmacological treatment, participated in a 12-week study. All patients were randomly allocated to a supplemented group (30g of an alkaline mineral supplement daily) or to an unsupplemented group. Their usual diet and medication was maintained. Disease activity, pain, and health-associated status were recorded (DAS 28 -Disease Activity Score 28, VAS -visual analogue scale for pain, HAQ -Health Assessment Questionnaire). Plasma immunoreactive endorphin (ir-EP) was measured in the study groups and also in healthy subjects. DAS 28 and VAS decreased in the supplemented group, whereas there was no change in these parameters during the trial in the control group. The functions (HAQ) of the supplemented patients improved. The ir-EP levels increased in both groups but to a higher degree in the supplemented group. During the trial, medication (NSAIDs and steroids) could be reduced in the supplemented group only. Conclusion: This study suggests that an alkaline supplement may improve function and pain in rheumatoid arthritis and may represent an easy and safe addition to the usual treatment of RA patients.

Chronic Sub-Clinical Systemic Metabolic Acidosis – A Review with Implications for Clinical Practice

“…3 Wu et al (2007) determined that even a minor alteration in extracellular pH may have significant impact on metabolism and the biosynthetic ability of chondrocytes with a maximum glycosaminoglycan synthesis occurring at a pH of 7.2. 115 Research studies have shown that chronic low back pain, 116 rheumatoid arthritis 117 and osteoarthritis of the hands 3 respond favorably to alkaline mineral supplementation (discussed below).…”

“…Studies addressing CSSMA and its consequences through supplementation generally apply one or a combination of alkalizing minerals as interventions (see supplementary data – Table 5). The most frequently applied alkaline minerals in the clinical trials include bicarbonate and the citrate salts: Potassium citrate 3,11,38–40,88,116,117,142,143 Potassium bicarbonate 3,7,10,41,43 Sodium bicarbonate 10,76,77,116,117,126,129,144,145 Calcium citrate 3,116,117 Magnesium citrate 3,116,117 Other citrate salts 116,117 …”

Säure-Basen-Haushalt und Gelenkerkrankungen

“…In Zusammenarbeit mit Kollegen von der Universität Budapest führten wir an einer dortigen spezialisierten Rheumaklinik eine Untersuchung zur Wirksamkeit eines Basenpräparats bei Patienten mit chronischer rheumatoider Arthritis durch. Die Ergebnisse zeigten, dass die Einnahme des Basenpräparats eine erhebliche Verminderung der Schmerzprobleme mit sich brachte [16]. Die Lebensqualität der Patienten verbesserte sich -gegenüber Patienten der Kontrollgruppe ohne Supplementierung -wesentlich und auch die Einnahme von schmerz-und entzündungshemmenden Medikamenten konnte durch die Basentherapie reduziert werden.…”

RegEnergetik – neue Energie durch Regeneration

“…Studien zeigen, dass bei rheumatoider Arthritis die Entzündung und die Schmerzen umso intensiver sind, je saurer die Gelenkfl üssigkeit ist [7]. Andere Untersuchungen belegen im Gegenzug, dass durch die Nahrungsergänzung mit basischen Citraten die Schmerzsymptomatik bei chronischen Rückenschmerzen [8] und bei rheumatoider Arthritis [9] deutlich gelindert werden kann. [22].…”