Alkalireserve des Blutes bei Leberkrankheiten

Responses to the Injection of Epinephrine in Hepatic Disease

“…They have also pointed out that epinephrine hyperglycemia results from an initial but transient glycogenolysis in the liver and that the hyperglycemia is then maintained by the decreased glucose utilization on the part of the muscles. 19 On the basis of the work described, numerous clinical studies have been made on the behavior of the lactic acid and of the blood sugar in the presence of liver disease (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). In general it has been slhown that: (a) the lactic acid content of the blood is increased in patients with severe liver disease; (b) there is a delay in the disappearance df sodium lactate injected intravenously; (c) feeding of sodium lactate occasionally raises the blood lactic acid level more in patients with liver disease than in normal individuals; (d) the hyperglycemia following the injection of epinephrine is less marked in cases of hepatic insufficiency than in those with normal livers, probably because of decreased glycogen stores.…”

The Lactic Acid of the Blood in Hepatic Disease 1

“…A number of papers (1,2,3,4,6,10,14,20,21,23,28,29,33,34, 35, 36) on the value for lactic acid in the blood in cases of hepatic disease and in experimental hepatic injury have appeared in the last few years. Although there are variations in the methods used and in the results obtained, most investigators agree that in the more severe degrees of hepatic injury, there is an increase in the lactic acid of the blood.…”