2005
DOI: 10.1016/j.phytochem.2005.02.010
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Alkaloids of Aconitum laeve and their anti-inflammatory, antioxidant and tyrosinase inhibition activities

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Cited by 88 publications
(41 citation statements)
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“…Although antioxidant activity of alkaloids is also documented (Shaheen et al, 2005;Oloyede et al, 2010;Maiza-Benabdesselam et al, 2007), these compounds did not have a reputation as good antioxidant agents; even those of pyridine type, like nicotine, are rather credited with pro-oxidant activity (Sudheer et al, 2005). This is in accordance with the results obtained in the present study.…”
Section: Resultssupporting
confidence: 90%
See 1 more Smart Citation
“…Although antioxidant activity of alkaloids is also documented (Shaheen et al, 2005;Oloyede et al, 2010;Maiza-Benabdesselam et al, 2007), these compounds did not have a reputation as good antioxidant agents; even those of pyridine type, like nicotine, are rather credited with pro-oxidant activity (Sudheer et al, 2005). This is in accordance with the results obtained in the present study.…”
Section: Resultssupporting
confidence: 90%
“…Antioxidants are known to suppress inflammation in a rat arthritis model and in a mouse model of contact hypersensitivity (Yoshino et al, 2006). Other studies indicate that alkaloids and especially phenolics contained in medicinal plants have antioxidant and/or anti-inflammatory activity (Kao et Shaheen et al, 2005). Relationship between these two biological activities has also been established (Scalbert et al, 2005;Jensen et al, 2008).…”
Section: Introductionmentioning
confidence: 97%
“…Computer matching against commercial (Wiley GC/MS Library; Adams Library; MassFinder 3 Library) (Jennings & Shibamoto, 1980;Adams, 2001;König et al, 2004) and in-house Başer Library of Essential Oil Constituents built up by genuine compounds and components of the known oils, as well as MS literature data (Joulain & König, 1988;McLafferty & Stauffer, 1989;ESO, 2000;Shaheen et al, 2005) were employed in identification of essential oil composition.…”
Section: Identification Of Componentsmentioning
confidence: 99%
“…Inhibition increased linearly with increasing concentration of the extract to a maximum effect of 95% inhibition of contractions at 0.25 mg/mL final bath concentration (Table 1). Alkaloids have been reported to be the principal class of constituents from A. laeve (Ulubelen et al, 2002;Shaheen et al, 2005). Indeed, phytochemical studies of this extract have led us to the isolation of several alkaloids; the exact structures of which are currently under investigation.…”
Section: Antispasmodic Activities Of the Selected Plantsmentioning
confidence: 99%