ALKALOIDS OF Astragalus kahiricus DC. PLANT ROOTS

Abstract

While looking for the toxic principle of Astragalus kahiricus DC., a herb highly toxic in livestock especially in small ruminants, hypaphorine, the N,N,N-trimethyl tryptophan betaine was isolated. This alkaloid was identified in Astragalus kahiricus, using NMR and MS methods. It was synthesized in sufficient amount and tested for potential toxicity in mice and lambs. In this study it is shown, with good evidence, that hypaphorine could not be held responsible for Astragalus kahiricus poisonings in small ruminants.

Phytochemical analysis and anticancer screening of some indigenous plants grown in Saudi Arabia

“…Some selected alkaloids and flavonoids isolated from R. stricta showed an@microbial and an@cancer proper@es (Nabih et al, 2012). Mohamed et al (2009) declared that Astragalus kahiricus DC., a herb highly toxic in livestock with very promising hepatoprotec@ve effect against ethanolinduced liver apoptosis (Allam et al, 2013).…”