Alkohol induzierte kognitive Dysfunktion

Abstract

Previous studies could show a complex relationship between alcohol consumption and cognition but also with processes of ageing both social and biological. Acute effects of alcohol during intoxication include clinical signs such as excitation and reduced inhibition, slurred speech, and increased reaction time but also cognitive dysfunction, especially deficits in memory functions. However, these cognitive deficits during alcohol intoxication are reversible while patients with alcohol addiction and chronic alcohol intake show severe impairments of cognitive functions especially deficits in executive functions. Frontal executive impairments in these patients include deficits in problem solving, abstraction, planning, organizing, and working memory.Additionally, gender specific deficits are relevant for the course of the disease and its concomitant health problems with female alcoholics showing a higher vulnerability for cognitive dysfunction and brain atrophy at earlier stages of alcoholism history.

Exploring Cannabis and Alcohol Co-Use in Adolescents: A Narrative Review of the Evidence

“…the effects of cannabis on cognitive function in both adults adolescents are somewhat nuanced (Gorey, Kuhns, Smaragdi, Kroon, & Cousijn, 2019), with recent studies suggesting that cannabis is not associated with cognitive deficits across all domains (Broyd, van Hell, Beale, Yücel, & Solowij, 2016;Scott et al, 2018), alcohol has a well-established negative impact on performance across nearly all domains of cognition (Weiss, Singewald, Ruepp, & Marksteiner, 2014). Although cannabis and alcohol are frequently used together, few human studies have examined the effects of cannabis and alcohol co-use on cognition, and none have tested this relationship in adolescents.…”

Differenzialdiagnosen bei demenzieller Entwicklung

“…Hierfür stehen Testbatterien wie das Minimal Assessment of Cognitive Function In MS (MACFIMS) oder die Testbatterie des MS-COG zur neuropsychologischen Verlaufsbeurteilung zur Verfügung. Tests mit der höchsten Sensitivität sind dabei u. a. der Symbol Digit Modality Test (SDMT), der sowohl zur Erst-wie auch Verlaufsbeurteilung der kognitiven Verarbeitungsgeschwindigkeit herangezogen werden kann [4].…”

“…Die multiple Sklerose ist eine demyelinisierende Autoimmunerkrankung des ZNS, bei der Betroffene im Verlauf alltagsrelevante kognitive Defizite entwickeln können. Dazu zählt u. a. eine verlangsamte Verarbeitungsgeschwindigkeit sowie Störungen des episodischen Gedächtnisses, der Exekutive, der Wortflüssigkeit und der visuell-räumlichen Fähigkeiten [4]. Hierfür stehen Testbatterien wie das Minimal Assessment of Cognitive Function In MS (MACFIMS) oder die Testbatterie des MS-COG zur neuropsychologischen Verlaufsbeurteilung zur Verfügung.…”

Comparing self-affirmation manipulations to reduce alcohol consumption in university students

“…It can also lead to psychiatric disorders, such as alcohol dependence, depression and anxiety (11,(19)(20)(21)(22). Binge drinking can further cause deficits in executive function, such as attention, memory or problemsolving (23)(24)(25) and, as a result, has been linked to poor academic achievement (26).…”