The removal effect on excessive fusel alcohols from rice spirits were investigated using nanofiltration (NF) and ultrafiltration (UF). Compared to UF (GE and GH membranes), NF (DK and DL membranes) showed 10 times greater effect for fusel alcohols rejection due to molecular weight cut-off. On operating pressures, 488.95 kPa was suitable with a rejection rate attaining 44.2% for DK membrane. Only slight changes in physicochemical indices including ethanol concentration, flavor, total acidity, pH value, and soluble solid content were observed for rice-spirits after NF treatment. Moreover, rice spirits treated with the DK membrane achieved a higher score in sensory evaluation. We anticipated a practical application of the nonheat processes in rice spirits production.