Alkyl-1h-Benzo[d]imidazole Synthesis From Alkyl Bromides and 1,2-Benzenediamines by a Mild Domino Reaction

Abstract

A method was implemented for synthesis of 2-alkyl-1H-benzo[d]imidazole derivatives in dry medium. Starting reagents, 1,2-diaminobenzene derivatives and primary alkyl halides using pyridine N-oxide is converted into benzimidazoles. The protocol does not use catalyst and solvent. Simplicity and easy work-up are the important advantages of the method.