2020
DOI: 10.1089/dia.2019.0486
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All Insulin Pumps Are Not Equivalent: A Bench Test Assessment for Several Basal Rates

Abstract: Background and Aims: Continuous subcutaneous insulin infusion (CSII) is a widely adopted treatment for type 1 diabetes and is a component of an artificial pancreas. CSII accuracy is essential for glycemic control, however, this metric has not been given sufficient study, especially at the range of the lowest basal rates (BRs), which are commonly used in a pediatric population and in closed-loop systems (CLSs). Our study presents accuracy results of four off-the-shelf CSII systems using a new accurate method fo… Show more

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Cited by 8 publications
(6 citation statements)
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“…In the present analysis, increasing accuracy with larger insulin doses was observed for the new pumps for bolus as well as basal rate delivery, confirming several other investigations. [9][10][11] The mean deviation of boluses from target was less than 5% for all bolus sizes in all pumps.…”
Section: Discussionmentioning
confidence: 88%
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“…In the present analysis, increasing accuracy with larger insulin doses was observed for the new pumps for bolus as well as basal rate delivery, confirming several other investigations. [9][10][11] The mean deviation of boluses from target was less than 5% for all bolus sizes in all pumps.…”
Section: Discussionmentioning
confidence: 88%
“…An adequate test setting for tubeless pumps is still under debate, especially as conflicting results are reported for OP from different working groups using different experimental designs. [4][5][6][7][8][9][10][11] In our previous tests, OP was only compared to durable pumps and showed inferior accuracy, giving rise to doubts about the experimental set-up. However, since the same delivery patterns, (large and recurrent variation between 1-h windows), were only observed in one of the two new pumps tested with the same setup, and as parts of the newly obtained results were comparable to those of durable pumps, these methodological doubts are now diminished.…”
Section: Discussionmentioning
confidence: 99%
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“…The in vitro accuracy of patch pumps, especially OP, has been examined previously and a generally decreased accuracy was found in comparison to durable pumps. 3,[12][13][14][15] However, a similarly detailed assessment of the time course of insulin delivery has not been carried out. A limitation of the present study is that the tested scenarios of constant basal delivery and consecutive bolus delivery are not particularly realistic.…”
Section: Discussionmentioning
confidence: 99%