The aim of the work is to develop a methodology for optimizing the work schedule under the production program of the construction company. The sample was selected based on deterministic mathematical methods and modelling. In particular, the method of processing expert opinions (method of expert evaluation) is used in this study to assess the actual degree of influence of each of the factors and its group on production indicators of the construction company. Methods of organizational and technological modelling, elements of systems theory, elements of systematics, construction system engineering were also used. A method of building and optimizing the work schedule under the production program of the construction company was developed during this study. This was implemented based on the concentration and regulation of labor resources of production units at dispersed start-up complex, as well as the maximum use of internal reserves of production units. This technique ensures the development of typical optimization solutions aimed at balanced resource consumption and effective fulfillment of the terms of construction contracts. Prospects for further research are based on the development of software in compliance with the presented methodology.